Search Results for "handbook-of-synthetic-organic-chemistry"

Handbook of Synthetic Organic Chemistry

Handbook of Synthetic Organic Chemistry

  • Author: Michael C. Pirrung
  • Publisher: Academic Press
  • ISBN: 0128095040
  • Category: Science
  • Page: 288
  • View: 7889
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Handbook of Synthetic Organic Chemistry, Second Edition updates and expands the author’s popular 2007 work, Synthetic Organic Chemist’s Companion. This new handbook provides valuable, practical guidance; incorporates corrections, and includes coverage on important topics, such as lyophylization, crystallization, precipitation, HPLC detectors, gases, and microwave reactions. The book maintains the useful organization of the author’s earlier work, beginning with a basic overview and walking through every practical step of the process of organic synthesis, from reagents, solvents, and temperature control, to documentation, implementation, purification, and analytical methods for the product. From planning and setting up reactions, to recording them, the book provides insight and valuable guidance into every step of the process. Practical guidance for planning, working up, documenting, analyzing, and improving reactions in synthetic organic chemistry

Handbook of Reagents for Organic Synthesis

Handbook of Reagents for Organic Synthesis

Reagents for Organocatalysis

  • Author: Tomislav Rovis
  • Publisher: John Wiley & Sons
  • ISBN: 1119061016
  • Category: Science
  • Page: 816
  • View: 8326
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Spurred by the desire to make chemistry a sustainable and "greener" technology, the field of organocatalysis has grown to become one of the most important areas in synthetic organic chemistry. Organic catalysts can often replace potentially toxic metal catalysts and allow reactions to proceed under mild reaction conditions, thereby saving energy costs and rendering chemical processes inherently safer. More importantly perhaps, organocatalysis offers a complementary reactivity in many instances leading to increased versatility. This Handbook describes 126 key reagents for organocatalytic reactions and will be especially useful for professionals in the area of sustainable chemistry, medicinal research, as well as synthetic organic chemists working in academia and the pharmaceutical industry. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 126 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.

Handbook of Organopalladium Chemistry for Organic Synthesis, 2 Volume Set

Handbook of Organopalladium Chemistry for Organic Synthesis, 2 Volume Set

  • Author: Ei-ichi Negishi
  • Publisher: John Wiley & Sons
  • ISBN: 0471461555
  • Category: Science
  • Page: 3424
  • View: 9271
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Handbook of Reagents for Organic Synthesis

Handbook of Reagents for Organic Synthesis

Reagents for Heteroarene Functionalization

  • Author: André B. Charette
  • Publisher: John Wiley & Sons
  • ISBN: 1118726553
  • Category: Science
  • Page: 824
  • View: 429
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Heteroarenes are among the most prevalent structural units in natural products, pharmaceuticals, agrochemicals, and other compounds of scientific or commercial interest. In the last decade, a broad range of novel synthetic methods has been developed to not only facilitate construction of the heteroarene motif, but to enable its modification through direct C?H functionalization. This Handbook describes 117 key reagents for selective heteroarene functionalization reactions, including both traditional and transition metal-catalyzed C?H functionalization. Since these reactions typically involve one heteroarene, a coupling partner and a catalyst, the handbook not only focuses on the catalyst itself but also contains other key reaction species. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 117 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.

Handbook of Reagents for Organic Synthesis, Reagents for Radical and Radical Ion Chemistry

Handbook of Reagents for Organic Synthesis, Reagents for Radical and Radical Ion Chemistry

  • Author: David Crich
  • Publisher: Wiley
  • ISBN: 9780470065365
  • Category: Science
  • Page: 722
  • View: 8175
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Handbook of Reagents for Organic Synthesis, Catalyst Components for Coupling Reactions

Handbook of Reagents for Organic Synthesis, Catalyst Components for Coupling Reactions

  • Author: Gary A. Molander
  • Publisher: John Wiley & Sons
  • ISBN: 1118643437
  • Category: Science
  • Page: 480
  • View: 7008
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The long awaited Handbook for all synthetic chemists working on coupling reactions, compiling all major catalyst components in use in the area. Consists of a compilation of articles taken from the EROS database, with the inclusion of about 20 newly commissioned catalysts/pre-catalysts/ligands that have made an impact in this area of synthetic organic chemistry. Includes catalyst systems used in Heck, Kumada-Tamao-Corriu, Suzuki-Miyaura, Hiyama-Hatanaka, Negishi, Migita-Kosugi-Stille, Buchwald-Hartwig, and Tsuji-Trost coupling reactions.

Handbook of Synthetic Photochemistry

Handbook of Synthetic Photochemistry

  • Author: Angelo Albini,Maurizio Fagnoni
  • Publisher: John Wiley & Sons
  • ISBN: 9783527628209
  • Category: Science
  • Page: 464
  • View: 363
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Unique in its focus on preparative impact rather than mechanistic details, this handbook provides an overview of photochemical reactions classed according to the structural feature that is built in the photochemical step, so as to facilitate use by synthetic chemists unfamiliar with this topic. An introductory section covers practical questions on how to run a photochemical reaction, while all classes of the most important photocatalytic reactions are also included. Perfect for organic synthetic chemists in academia and industry.

Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis

Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis

  • Author: Philip L. Fuchs
  • Publisher: John Wiley & Sons
  • ISBN: 1118636139
  • Category: Technology & Engineering
  • Page: 816
  • View: 4602
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Over the last three decades the importance of organosilicon chemistry has greatly increased because it has opened a number of new synthetic strategies. Silicon reagents are usually low-cost, versatile and allow a wide range of reactions. This is the first Handbook to compile essential Silicon containing reagents and makes use of the leading reagent database e-EROS. Another hot volume in the series Handbooks of Reagents for Organic Synthesis, this is a must-have resource for all synthetic chemists working in drug development and medicinal chemistry. For the selection the Editor focussed on three key synthetic approaches with the greatest impact: 1. Use of silicon as a 'temporary tether' by unifying a reactive pair of functional groups and taking advantage of their template-biased intramolecular cyclization. 2. The specific use of the silane functionality as a hetero t-butyl group, often colloquially referred to as the use of silicon as a 'fat proton'. 3. The use of the Brook rearrangement as an 'anion relay stratagem'. A new feature in this Handbook is the reagent finder, an alphabetically organized lookup table arranged by organic functionality and specific structure of the silicon atom to which it is bound.

Handbook of Metathesis, Volume 2

Handbook of Metathesis, Volume 2

Applications in Organic Synthesis

  • Author: Robert H. Grubbs,Daniel J. O'Leary
  • Publisher: John Wiley & Sons
  • ISBN: 3527694048
  • Category: Science
  • Page: 744
  • View: 2721
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The second edition of the "go-to" reference in this field is completely updated and features more than 80% new content, with emphasis on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality. Edited by the Nobel laureate R. H. Grubbs and D. J. O´Leary, Volume 2 of the 3-volume work focusses on applications in organic synthesis. With a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for chemists in academia and industry. View the set here - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527334246.html Other available volumes: Volume 1: Catalyst Development and Mechanism, Editors: R. H. Grubbs and A. G. Wenzel - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339485.html Volume 3: Polymer Synthesis, Editors: R. H. Grubbs and E. Khosravi - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339507.html

Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis

Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis

  • Author: Shigeo Nishimura
  • Publisher: Wiley-Interscience
  • ISBN: 9780471396987
  • Category: Science
  • Page: 720
  • View: 5739
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The most comprehensive reference in the field, Handbook of Heterogeneous Catalytic Hydrogenation for Organic Synthesis provides synthetic chemists and chemical engineers in fine chemicals and pharmaceuticals with detailed experimental guidelines for heterogeneous catalytic hydrogenation. Organized by functional groups for ready reference and featuring detailed examples of hundreds of reactions, this handbook covers hydrogenations of alkenes, alkynes, aldehydes and ketones, nitriles, imines, nitro and nitroso compounds, carboxylic acids and esters, and aromatic and heterocyclic compounds. In addition, coverage includes the preparation of amines by reductive alkylation and the hydrogenolysis of a variety of compounds. Examples of hydrogenation of functional groups and reaction pathways are illustrated with numerous equations and schemes. Practitioners will appreciate the plenitude of experimental details given for most of the reactions selected, including amounts of reagents and catalysts, reaction temperatures, hydrogen pressures, and reaction times. They will also find helpful the more than one hundred tables included throughout the book detailing the effects of key factors governing rate and selectivity, such as compound structure, the nature of catalysts and supports, and the nature of solvents. Researchers will benefit from the introductory chapters covering an array of hydrogenation catalysts, including nickel, cobalt, copper, iron, platinum group metals, rhenium, and other oxide and sulfide catalysts, as well as reactors and reaction conditions.

Handbook of Metathesis, Volume 3

Handbook of Metathesis, Volume 3

Polymer Synthesis

  • Author: Robert H. Grubbs,Ezat Khosravi
  • Publisher: John Wiley & Sons
  • ISBN: 3527694056
  • Category: Science
  • Page: 424
  • View: 6910
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The second edition of the "go-to" reference in this field is completely updated and features more than 80% new content, with emphasis on new developments in the field, especially in industrial applications. No other book covers the topic in such a comprehensive manner and in such high quality. Edited by the Nobel laureate R. H. Grubbs and E. Khosravi, Volume 3 of the 3-volume work focusses on polymer synthesis. With a list of contributors that reads like a "Who's-Who" of metathesis, this is an indispensable one-stop reference for chemists in academia and industry. View the set here - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527334246.html Other available volumes: Volume 1: Catalyst Development and Mechanism, Editors: R. H. Grubbs and A. G. Wenzel - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339485.html Volume 2: Applications in Organic Synthesis, Editors: R. H. Grubbs and D. J. O´Leary - http://www.wiley.com/WileyCDA/WileyTitle/productCd-3527339493.html

Linker Strategies in Solid-Phase Organic Synthesis

Linker Strategies in Solid-Phase Organic Synthesis

  • Author: Peter Scott
  • Publisher: John Wiley & Sons
  • ISBN: 9780470749050
  • Category: Science
  • Page: 706
  • View: 9565
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Linker design is an expanding field with an exciting future in state-of-the-art organic synthesis. Ever-increasing numbers of ambitious solution phase reactions are being adapted for solid-phase organic chemistry and to accommodate them, large numbers of sophisticated linker units have been developed and are now routinely employed in solid-phase synthesis. Linker Strategies in Solid-Phase Organic Synthesis guides the reader through the evolution of linker units from their genesis in solid-supported peptide chemistry to the cutting edge diversity linker units that are defining a new era of solid phase synthesis. Individual linker classes are covered in easy to follow chapters written by international experts in their respective fields and offer a comprehensive guide to linker technology whilst simultaneously serving as a handbook of synthetic transformations now possible on solid supports. Topics include: the principles of solid phase organic synthesis electrophile and nucleophile cleavable linker units cyclative cleavage as a solid phase strategy photocleavable linker units safety-catch linker units enzyme cleavable linker units T1 and T2 –versatile triazene linker groups hydrazone linker units benzotriazole linker units phosphorus linker units sulfur linker units selenium and tellurium linker units sulfur, oxygen and selenium linker units cleaved by radical processes silicon and germanium linker units boron and stannane linker units bismuth linker units transition metal carbonyl linker units linkers releasing olefins or cycloolefins by ring-closing metathesis fluorous linker units solid-phase radiochemistry The book concludes with extensive linker selection tables, cataloguing the linker units described in this book according to the substrate liberated upon cleavage and conditions used to achieve such cleavage, enabling readers to choose the right linker unit for their synthesis. Linker Strategies in Solid-Phase Organic Synthesis is an essential guide to the diversity of linker units for organic chemists in academia and industry working in the broad areas of solid-phase organic synthesis and diversity oriented synthesis, medicinal chemists in the pharmaceutical industry who routinely employ solid-phase chemistry in the drug discovery business, and advanced undergraduates, postgraduates, and organic chemists with an interest in leading-edge developments in their field.

The Handbook of Medicinal Chemistry

The Handbook of Medicinal Chemistry

Principles and Practice

  • Author: Andrew Davis,Simon E Ward
  • Publisher: Royal Society of Chemistry
  • ISBN: 1782621830
  • Category: Technology & Engineering
  • Page: 753
  • View: 7277
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Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development. A free iPad app has been created in collaboration with the editors of the book. The Medicinal Chemistry Toolkit provides a suite of resources to support the day to day work of a medicinal chemist. Search for "Medicinal Chemistry Toolkit."

Fluorine-Containing Reagents

Fluorine-Containing Reagents

  • Author: Leo A. Paquette
  • Publisher: Wiley-Interscience
  • ISBN: 9780470021774
  • Category: Science
  • Page: 730
  • View: 9805
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Another hot-topic volume in the Handbook of Reagents for Organic Synthesis series! This is the first book with all relevant Fluorine containing reagents, and it is an important addition to the vast list of existing books on organic and inorganic Fluorine synthesis. Synthetic chemists, most particularly medicinal and pharmaceutical chemists, are often called upon to prepare compounds that contain Fluorine as a key structural feature. In the past, this seemed to be a domain for specialists, today every synthetic chemist working in these area is expected to synthesize compounds containing Fluorides. This book will be an important source of information for the selection and handling of the right reagents. A must-to-have resource for all synthetic chemists working in drug development and medicinal chemistry Makes use of the leading reagent database e-EROS.

Room Temperature Organic Synthesis

Room Temperature Organic Synthesis

  • Author: Goutam Brahmachari
  • Publisher: Elsevier
  • ISBN: 0128011386
  • Category: Science
  • Page: 386
  • View: 6560
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Filling a gap in the scientific literature, Room Temperature Organic Synthesis is unique in its authoritative, thorough, and applied coverage of a wide variety of "green" organic synthetic methodologies. The book describes practical, feasible protocols for room temperature reactions to produce carbon-carbon and carbon-heteroatom bond formations including aliphatic, aromatic, alicyclic, heterocycles, and more. Consistently organized for easy access, each selected reaction is discussed in a very compact and structured manner including: reaction type, reaction condition, reaction strategy, catalyst, keywords, general reaction scheme, mechanism (in selected cases), representative entries, experimental procedure, characterization data of representative entries, and references. This book will be a valuable resource for synthetic organic, natural products, medicinal, and biochemists as well as those working in the pharmaceutical and agrochemical industry. Includes more than 300 protocols for a green approach to organic synthesis Provides specific detail about experimental conditions Increases efficiency in the laboratory by eliminating time-consuming literature searches

Handbook of Reagents for Organic Synthesis, Reagents for Radical and Radical Ion Chemistry

Handbook of Reagents for Organic Synthesis, Reagents for Radical and Radical Ion Chemistry

  • Author: David Crich
  • Publisher: John Wiley & Sons
  • ISBN: 1118634896
  • Category: Science
  • Page: 728
  • View: 875
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Radicals and radical ions are important intermediates with wide use in organic synthesis. The first book to concentrate on reagents for the creation and use of radicals and radical ions, this new volume in the Handbooks of Reagents for Organic Synthesis series compiles articles taken from the e-eros database, on reagents for use in radical and radical chemistry, to help the chemist in the lab choose the right reagents. Reflecting the enormous growth of radical chemistry over the past ten years, this is an essential guide for all synthetic chemists.

Handbook of Palladium-catalyzed Organic Reactions

Handbook of Palladium-catalyzed Organic Reactions

Synthetic Aspects and Catalytic Cycles

  • Author: Jean-Luc Malleron,J. C. Fiaud,Jean-Yves Legros
  • Publisher: N.A
  • ISBN: 9780124666153
  • Category: Science
  • Page: 304
  • View: 310
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Organometallic chemistry; Palladium chemistry - Graphical abstracts of reaction numbers (RXN); Reactions catalysed by palladium complexes.

Organische Chemie

Organische Chemie

  • Author: Jonathan Clayden,Nick Greeves,Stuart Warren
  • Publisher: Springer Spektrum
  • ISBN: 9783642347153
  • Category: Science
  • Page: 1366
  • View: 4951
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Ein neuer Stern am Lehrbuch-Himmel: Organische Chemie von Clayden, Greeves, Warren - der ideale Begleiter für alle Chemiestudenten. Der Schwerpunkt dieses didaktisch durchdachten, umfassenden vierfarbigen Lehrbuches liegt auf dem Verständnis von Mechanismen, Strukturen und Prozessen, nicht auf dem Lernen von Fakten. Organische Chemie entpuppt sich als dabei als ein kohärentes Ganzes, mit zahlreichen logischen Verbindungen und Konsequenzen sowie einer grundlegenden Struktur und Sprache. Dank der Betonung von Reaktionsmechanismen, Orbitalen und Stereochemie gewinnen die Studierenden ein solides Verständnis der wichtigsten Faktoren, die für alle organisch-chemischen Reaktionen gelten. So lernen sie, auch Reaktionen, die ihnen bisher unbekannt waren, zu interpretieren und ihren Ablauf vorherzusagen. Der direkte, persönliche, studentenfreundliche Schreibstil motiviert die Leser, mehr erfahren zu wollen. Umfangreiche Online-Materialien führen das Lernen über das gedruckte Buch hinaus und vertiefen das Verständnis noch weiter.

Kent and Riegel's Handbook of Industrial Chemistry and Biotechnology

Kent and Riegel's Handbook of Industrial Chemistry and Biotechnology

  • Author: James A. Kent
  • Publisher: Springer Science & Business Media
  • ISBN: 0387278435
  • Category: Science
  • Page: 1875
  • View: 6346
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This substantially revised and updated classic reference offers a valuable overview and myriad details on current chemical processes, products, and practices. No other source offers as much data on the chemistry, engineering, economics, and infrastructure of the industry. The two volume Handbook serves a spectrum of individuals, from those who are directly involved in the chemical industry to others in related industries and activities. Industrial processes and products can be much enhanced through observing the tenets and applying the methodologies found in the book’s new chapters.

CRC Handbook of Organic Photochemistry and Photobiology, Volumes 1 & 2, Second Edition

CRC Handbook of Organic Photochemistry and Photobiology, Volumes 1 & 2, Second Edition

  • Author: William M. Horspool,Francesco Lenci
  • Publisher: CRC Press
  • ISBN: 9780203495902
  • Category: Science
  • Page: 2904
  • View: 8091
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The second edition of this best-selling handbook is bigger, more comprehensive, and now completely current. In addition to thorough updates to the discussions featured in the first edition, this edition includes 66 new chapters that reflect recent developments, new applications, and emerging areas of interest. Within the handbook's 145 critically reviewed chapters, leading experts from around the world present fundamental concepts, cutting-edge research, and up-to-date tables of physical data. The CRC Handbook of Organic Photochemistry and Photobiology, Second Edition is simply the most authoritative and complete resource available for these fields. New or updated topics in the Second Edition include: Photosensory Biology Phochemotherapy Photodynamic Therapy Photoecology Photosynthesis Photomovements Phototropism Photomorphogenesis Optobioelectronics Biomolecular Photonics Spectroscopy