Search Results for "modern-sample-preparation-for-chromatography"

Modern Sample Preparation for Chromatography

Modern Sample Preparation for Chromatography

  • Author: Serban C. Moldoveanu,Victor David
  • Publisher: Elsevier
  • ISBN: 0444543228
  • Category: Science
  • Page: 453
  • View: 5412
DOWNLOAD NOW »
Sample preparation is applied to make real world samples amenable for chromatographic analysis, or to improve the results of this type of analysis. A wide variety of procedures are applied for this purpose, and their description is the main goal of the present book. The principles of these procedures are explained, discussing their advantages and disadvantages, and their applicability to different types of samples as well as their fit for different types of chromatographic analysis. This provides a guide for choosing the appropriate sample preparation for a given analysis. The book also contains numerous literature references and examples of sample preparation for different matrices. The material is presented in three parts, one discussing physical methods used in sample preparation such as filtration, distillation, solvent extraction, solid phase extraction, electro-separations. Presents in a systematic way numerous techniques applied for sample preparation for chromatographic analysis Provides an up to date source of information regarding the progress made in sample preparation for chromatography Describes examples for specific type of matrices, providing a guide for choosing the appropriate sample preparation method for a given analysis

Sampling and Sample Preparation in Field and Laboratory

Sampling and Sample Preparation in Field and Laboratory

Fundamentals and New Directions in Sample Preparation

  • Author: Janusz Pawliszyn
  • Publisher: Elsevier
  • ISBN: 9780444505101
  • Category: Science
  • Page: 1131
  • View: 9324
DOWNLOAD NOW »
This title is the first comprehensive book on sampling and modern sample preparation techniques and has several main objectives: to facilitate recognition of sample preparation as both an integral part of the analytical process; to present a fundamental basis and unified theoretical approach for the professional development of sample preparation; to emphasize new developments in sample preparation technology; and to highlight the future impact of sample preparation on new directions in analytical science, particularly automation, miniaturization and field implementation. Until recently, there has been relatively little scientific interest in sampling and sample preparation, however this situation is presently changing as sampling and sample preparation become integral parts of the analytical process with their own unique challenges and research opportunities. Sampling and Sample Preparation for Field and Laboratory is an essential resource for all analytical chemists, and in particular those involved in method development. Not only does it cover the fundamental aspects of extraction, it also covers applications in various matrices and includes sampling strategies and equipment and how these can be integrated into the analytical process for maximum efficiency.

Analytische Chemie

Analytische Chemie

Grundlagen, Methoden und Praxis

  • Author: Georg Schwedt,Torsten C. Schmidt,Oliver J. Schmitz
  • Publisher: John Wiley & Sons
  • ISBN: 3527698795
  • Category: Science
  • Page: 560
  • View: 8797
DOWNLOAD NOW »
Alle relevanten Aspekte der Analytischen Chemie werden in diesem Lehrbuch, das gleichzeitig auch als Referenz fï¿1⁄2r Praktiker dient, umfassend und klar auf den Punkt gebracht. Das Autorenteam wird durch zwei aktive und international bekannte Professoren verstï¿1⁄2rkt; dies sorgt fï¿1⁄2r frischen Wind, gleichzeitig wird der didaktisch ausgefeilte Stil der Vorauflagen beibehalten. Von der Analysenstrategie zur Probenvorbereitung, von der Maï¿1⁄2analyse ï¿1⁄2ber spektroskopische und chromatographische Methoden bis zur Automatisierung - DAS Lehrbuch fï¿1⁄2r alle, die sich mit Analytischer Chemie beschï¿1⁄2ftigen.

Comprehensive Sampling and Sample Preparation

Comprehensive Sampling and Sample Preparation

Analytical Techniques for Scientists

  • Author: Janusz Pawliszyn
  • Publisher: Academic Press
  • ISBN: 9780123813732
  • Category: Science
  • Page: 3200
  • View: 2204
DOWNLOAD NOW »
Although there is widespread information on sampling and sample preparation, it is not collected together in a comprehensive and accessible way. Approximately 30,000 new journal articles are published in this area each year, spread over a wide range of health science and physical science disciplines. Navigating this literature is time-consuming and as methods diverge, it's difficult to make the right choices. Users of Comprehensive Sample and Sample Preparation can feel confident that the information collected has been carefully reviewed and vetted, which means they can save time and make sound decisions on what can be used in their own work. In its four volumes, Comprehensive Sampling and Sample Preparation contains a complete treatment of the theory and methodology of sampling in all physical phases and the theory of sample preparation for all major extraction techniques. Fundamentals of sampling and sample preparation are reinforced through broad and detailed sections dealing with Biological and Medical, Environmental and Forensic, and Food and Beverage applications. The contributions are organized to reflect the way in which analytical chemists approach a problem. It is intended for a broad audience of analytical chemists, both educators and practitioners of the art and can assist in the preparation of courses as well in the selection of sampling and sample preparation techniques to address the challenges at hand. Sampling and Sample preparation is a large and well-defined field in Analytical Chemistry, relevant for many application areas such as medicine, environmental science, biochemistry, pharmacology, geology, and food science. This work covers all these aspects and will be extremely useful to researchers and students, who can use it as a starting point to design and implement their experiments and for quality-reviewed background information. There are limited resources that Educators can use to effectively teach the fundamental aspects of modern sample preparation technology. Comprehensive Sampling and Sample Preparation addresses this need, but focuses on the common principles of new developments in extraction technologies rather than the differences between techniques thus facilitating a more thorough understanding. Provides a complete overview of the field. Not only will help to save time, it will also help to make correct assessments and avoid costly mistakes in sampling in the process. Sample and sample preparation are integral parts of the analytical process but are often less considered and sometimes even completely disregarded in the available literature. To fill this gap, leading scientists have contributed 130 chapters, organized in 4 volumes, covering all modern aspects of sampling and liquid, solid phase and membrane extractions, as well as the challenges associated with different types of matrices in relevant application areas.

Modern Practice of Gas Chromatography

Modern Practice of Gas Chromatography

  • Author: Robert L. Grob, PhD,Eugene F. Barry, PhD
  • Publisher: John Wiley & Sons
  • ISBN: 9780471651154
  • Category: Science
  • Page: 1064
  • View: 1631
DOWNLOAD NOW »
The bible of gas chromatography-offering everything the professional and the novice need to know about running, maintaining, and interpreting the results from GC Analytical chemists, technicians, and scientists in allied disciplines have come to regard Modern Practice of Gas Chomatography as the standard reference in gas chromatography. In addition to serving as an invaluable reference for the experienced practitioner, this bestselling work provides the beginner with a solid understanding of gas chromatographic theory and basic techniques. This new Fourth Edition incorporates the most recent developments in the field, including entirely new chapters on gas chromatography/mass spectrometry (GC/MS); optimization of separations and computer assistance; high speed or fast gas chromatography; mobile phase requirements: gas system requirements and sample preparation techniques; qualitative and quantitative analysis by GC; updated information on detectors; validation and QA/QC of chromatographic methods; and useful hints for good gas chromatography. As in previous editions, contributing authors have been chosen for their expertise and active participation in their respective areas. Modern Practice of Gas Chromatography, Fourth Edition presents a well-rounded and comprehensive overview of the current state of this important technology, providing a practical reference that will greatly appeal to both experienced chomatographers and novices.

Liquid Chromatography

Liquid Chromatography

Applications

  • Author: Salvatore Fanali,Paul R. Haddad,Colin Poole,Marja-Liisa Riekkola
  • Publisher: Elsevier
  • ISBN: 0128093447
  • Category: Science
  • Page: 838
  • View: 5762
DOWNLOAD NOW »
Liquid Chromatography: Applications, Second Edition,is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their knowledge of the wide variety of applications in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Chromatography

Chromatography

Basic Principles, Sample Preparations and Related Methods

  • Author: Elsa Lundanes,Léon Reubsaet,Tyge Greibrokk
  • Publisher: John Wiley & Sons
  • ISBN: 3527675221
  • Category: Science
  • Page: 224
  • View: 646
DOWNLOAD NOW »
Finally a book on chromatography which is easy to grasp for undergraduates and technicians; covers the area in sufficient depth while still being concise. The book includes all recent technology advances and has core textbook features further improving the learning experience. This book is the perfect introduction into a methodology which is the underlying principle of the vast majority of separation methods worldwide. Everyone working in a lab environment must be familiar with the basis of these technologies and Tyge Greibrokk, Elsa Lundanes and Leon Reubsaet succeed in delivering a text which is easy to read for undergraduates and laboratory technicians, and covers the area in sufficient depth while still being concise. The book includes all recent technology advances and has core textbook features further improving the learning experience. Importantly, the text does not only cover all major modern chromatography technology (thin layer, gas, high pressure liquid, and supercritical fluid chromatography) but also related methods, in particular electrophoretic technologies.

Modern Chromatographic Analysis Of Vitamins

Modern Chromatographic Analysis Of Vitamins

Revised And Expanded

  • Author: Andre P. De Leenheer,Willy Lambert
  • Publisher: CRC Press
  • ISBN: 082474649X
  • Category: Science
  • Page: 632
  • View: 9176
DOWNLOAD NOW »
Third Edition collects and examines the tremendous proliferation of information on chromatographic analysis of fat and water soluble vitamins over the last decade. Extensively describes sample preparation and final measurement.

Modern Thin-Layer Chromatography

Modern Thin-Layer Chromatography

  • Author: Nelu Grinberg
  • Publisher: CRC Press
  • ISBN: 9780824781385
  • Category: Science
  • Page: 504
  • View: 3996
DOWNLOAD NOW »
Provides chemists with an in-depth account of chromatographic phenomena and a detailed reference guide to the various choices in optimizing chromatographic separations of enantiomers. Clarifies how thin-layer chromatography differs from, but can be used as a pilot procedure for, high-performance liq

Miniaturization in Sample Preparation

Miniaturization in Sample Preparation

  • Author: Francisco Pena Pereira
  • Publisher: Walter de Gruyter GmbH & Co KG
  • ISBN: 3110410184
  • Category: Science
  • Page: 463
  • View: 6651
DOWNLOAD NOW »
The miniaturization of traditional sample preparation techniques (e.g., solid-phase extraction or solvent extraction) led to the development of environmentally benign analytical methods. This book aims to provide an overview of the challenges and achievements in the application of the miniaturized sample preparation methods in analytical laboratories.

High Throughput Bioanalytical Sample Preparation

High Throughput Bioanalytical Sample Preparation

Methods and Automation Strategies

  • Author: David A. Wells
  • Publisher: Elsevier Science
  • ISBN: 9780444510297
  • Category: Science
  • Page: 610
  • View: 6439
DOWNLOAD NOW »
Several chapters introduce and discuss microplates, accessory products and automation devices. Particular strategies for efficient use of automation within a bioanalytical laboratory are also presented. The subject material then reviews protein precipitation, liquid-liquid extraction, solid-phase extraction and various on-line sample preparation approaches. The book concludes with information on recent advances in sample preparation, such as solid-phase extraction in a card format and higher density extraction plates. Important objectives that can be accomplished when the strategies presented in this book are followed include: improved efficiency in moving discovery compounds to preclinical status with robust analytical methods; return on investment in automation for sample preparation; and improved knowledge and expertise of laboratory staff.-

HPLC Method Development for Pharmaceuticals

HPLC Method Development for Pharmaceuticals

  • Author: Satinder Ahuja,Henrik Rasmussen
  • Publisher: Elsevier
  • ISBN: 0080554199
  • Category: Medical
  • Page: 532
  • View: 6419
DOWNLOAD NOW »
High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

High Performance Liquid Chromatography in Pesticide Residue Analysis

High Performance Liquid Chromatography in Pesticide Residue Analysis

  • Author: Tomasz Tuzimski,Joseph Sherma
  • Publisher: CRC Press
  • ISBN: 1466568828
  • Category: Science
  • Page: 582
  • View: 7320
DOWNLOAD NOW »
HPLC is the principal separation technique for identification of the pesticides in environmental samples and for quantitative analysis of analytes. At each stage of the HPLC procedure, the chromatographer should possess both the practical and theoretical skills required to perform HPLC experiments correctly and to obtain reliable, repeatable, and reproducible results. Developed to serve as a detailed practical guide, High Performance Liquid Chromatography in Pesticide Residue Analysis is a comprehensive source of information and training on state-of-the-art pesticide residue methods performed with the aid of HPLC. The book presents the pros and cons of HPLC as a flexible and versatile separation and analysis tool with multiple purposes and advantages in investigations of pesticides for food and plant drugs standardization, promotion of health, protection of new herbal medicines, and more.

EAAP Publication

EAAP Publication

  • Author: Antonius Franciscus Bernadus Poel,J. Huisman,H.S. Saini
  • Publisher: N.A
  • ISBN: 9789074134088
  • Category: Livestock
  • Page: 550
  • View: 641
DOWNLOAD NOW »

Modern Analytical Techniques

Modern Analytical Techniques

Analytical Methods for Pesticides and Plant Growth Regulators

  • Author: Gunter Zweig,Joseph Sherma
  • Publisher: Academic Press
  • ISBN: 1483220915
  • Category: Technology & Engineering
  • Page: 272
  • View: 3792
DOWNLOAD NOW »
Analytical Methods for Pesticides and Plant Growth Regulators, Volume XIV: Modern Analytical Techniques covers an updated treatment of the most frequently used techniques for pesticide analysis, i.e., thin-layer chromatography, gas chromatography (packed and capillary columns), high-performance liquid chromatography, and mass spectrometry. People involved in the analysis of pesticides will find the book useful.

Selective Sample Handling and Detection in High-Performance Liquid Chromatography

Selective Sample Handling and Detection in High-Performance Liquid Chromatography

  • Author: K. Zech,R.W. Frei†
  • Publisher: Elsevier
  • ISBN: 9780080858432
  • Category: Science
  • Page: 393
  • View: 454
DOWNLOAD NOW »
This is the second of a two-volume project which treats the handling, separation and detection of complex samples as an integrated, interconnected process. On the basis of this philosophy the editors have selected those contributions which demonstrate that optimal sample preparation leads to a simplification of detection or reduced demands on the separation process. Throughout the book emphasis is on chemical principles with minimum discussion of the equipment required - an approach which reflects the editors' view that the limiting factor in the analysis of complex samples is an incomplete knowledge of the underlying chemistry rather than the hardware available. This lack of knowledge becomes more evident as the demands for lower detection limits grow, as solving complex matrix problems requires a greater understanding of the chemical interaction between the substance to be analysed and the stationary phase. Thus, apart from one chapter dealing with chemically modified silicas, the main theme of the book is developed in three chapters on sample preparation and three on detection. The opening chapter outlines concentration and chromatography on chemically modified silicas with complexing properties, and gives examples of the use of these phases with organic and inorganic compounds. Chapter II, the first of the three contributions dealing with sample preparation, addresses such questions as whether the prepared sample is representative of the material to be analysed; how to avoid contamination; which separation procedure should be used to avoid tedious sample preparation. Chapter III describes the processing of whole blood for drug analysis. The determination of cyclosporine and its metabolites (an especially difficult case) demonstrates how comprehensive the optimisation of sample preparation must be to successfully perform the analysis. Several other examples are also given. Chapter IV deals with radio-column liquid chromatography and introduces the other theme of the book, i.e. selective detection methods. The widespread use of radioisotopes requires a high degree of purification during the manufacture of the compounds, as well as highly accurate detection methods in biological and biochemical studies. Chapter V continues the theme of selective detection with an overview of post-column reaction detection. The use of immobilised enzymes in post-column reactors or `pumpless' reactor systems for on-line reagent generation after the chromatographic separation step is discussed in detail. Various examples of the separation of biological compounds show how the production of electrochemical reagents and photochemical reaction detection have increased the selectivity of the detection, leading to more economical analytical systems. Selective detection employing luminescence detection techniques is outlined in Chapter VI. The use of immobilised fluorophores or the coupling to photochemical reactions leads to highly selective detection systems which can greatly simplify the sample handling. The final chapter reviews the use of continuous separation techniques in flow injection analysis thus revealing the need for a strong interdisciplinary dependence between sample handling and separation in this area. Written by experienced practitioners, this book will be extremely useful to investigators in many areas of application. Each chapter includes sufficient references to the literature to serve as a valuable starting point for more detailed investigation. The strong emphasis on sample handling makes the book unique in many ways and it will be welcomed by environmental scientists as well as those active in the clinical, pharmaceutical and bioanalytical fields.

Introduction to Modern Liquid Chromatography

Introduction to Modern Liquid Chromatography

  • Author: Lloyd R. Snyder,Joseph J. Kirkland,John W. Dolan
  • Publisher: John Wiley & Sons
  • ISBN: 1118210395
  • Category: Science
  • Page: 960
  • View: 7789
DOWNLOAD NOW »
The latest edition of the authoritative reference to HPLC High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as: The basis of HPLC separation and the general effects of different experimental conditions Equipment and detection The column—the "heart" of the HPLC system Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques Computer simulation, qualitative and quantitative analysis, and method validation and quality control The separation of large molecules, including both biological and synthetic polymers Chiral separations, preparative separations, and sample preparation Systematic development of HPLC separations—new to this edition Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.

Gas Chromatography

Gas Chromatography

  • Author: Colin Poole
  • Publisher: Elsevier
  • ISBN: 0123855411
  • Category: Science
  • Page: 688
  • View: 1311
DOWNLOAD NOW »
This title provides comprehensive coverage of modern gas chromatography including theory, instrumentation, columns, and applications addressing the needs of advanced students and professional scientists in industry and government laboratories. Chapters are written by recognized experts on each topic. Each chapter offers a complete picture with respect to its topic so researchers can move straight to the information they need without reading through a lot of background information. Individual chapters written by recognized experts The big picture of gas chromatography from theory, to methods, to selected applications Provides references to other sources in associated areas of study to facilitate research Gives access to core data for practical work, comparison of results and decision making

Environmental Geochemistry in Tropical and Subtropical Environments

Environmental Geochemistry in Tropical and Subtropical Environments

  • Author: Luiz Drude de Lacerda,Ricardo Erthal Santelli,Egbert K. Duursma,Jorge Joao Abrao
  • Publisher: Springer Science & Business Media
  • ISBN: 366207060X
  • Category: Nature
  • Page: 385
  • View: 3434
DOWNLOAD NOW »
This book incorporates twenty contributions on diverse aspects of the environmental geochemistry in tropical and sub-tropical environments, drawing together extensive original research not readily available elsewhere. Coverage includes intercontinental comparisons drawn on paleoclimatology, environmental impacts of mining and geochemistry of continetal shelf sediments.

Modern HPLC for Practicing Scientists

Modern HPLC for Practicing Scientists

  • Author: Michael W. Dong
  • Publisher: John Wiley & Sons
  • ISBN: 0471973092
  • Category: Science
  • Page: 320
  • View: 1825
DOWNLOAD NOW »
A comprehesive yet concise guide to Modern HPLC Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers. Topics covered include: HPLC operation Method development Maintenance and troubleshooting Modern trends in HPLC such as quick-turnaround and "greener" methods Regulatory aspects While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources. With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.