Search Results for "practical-process-research-and-development-a-guide-for-organic-chemists-second-edition"

Practical Process Research and Development

Practical Process Research and Development

A Guide for Organic Chemists

  • Author: Neal G. Anderson
  • Publisher: Academic Press
  • ISBN: 0123865379
  • Category: Science
  • Page: 475
  • View: 7338
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Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights: • Reflects the current thinking in chemical process R&D for small molecules • Retains similar structure and orientation to the first edition. • Contains approx. 85% new material • Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up) • Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes) • Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more Presents guidelines for implementing and troubleshooting processes

Handbook of Synthetic Organic Chemistry

Handbook of Synthetic Organic Chemistry

  • Author: Michael C. Pirrung
  • Publisher: Academic Press
  • ISBN: 0128095040
  • Category: Science
  • Page: 288
  • View: 7719
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Handbook of Synthetic Organic Chemistry, Second Edition updates and expands the author’s popular 2007 work, Synthetic Organic Chemist’s Companion. This new handbook provides valuable, practical guidance; incorporates corrections, and includes coverage on important topics, such as lyophylization, crystallization, precipitation, HPLC detectors, gases, and microwave reactions. The book maintains the useful organization of the author’s earlier work, beginning with a basic overview and walking through every practical step of the process of organic synthesis, from reagents, solvents, and temperature control, to documentation, implementation, purification, and analytical methods for the product. From planning and setting up reactions, to recording them, the book provides insight and valuable guidance into every step of the process. Practical guidance for planning, working up, documenting, analyzing, and improving reactions in synthetic organic chemistry

The Chemistry of Process Development in Fine Chemical and Pharmaceutical Industry

The Chemistry of Process Development in Fine Chemical and Pharmaceutical Industry

  • Author: Someswara Rao
  • Publisher: Wiley
  • ISBN: 9780470319956
  • Category: Technology & Engineering
  • Page: 1328
  • View: 9590
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This book brings together the chemical strategies used in the optimisation of organic reactions and processes, and highlights the practical and technological options available. This book offers: an encyclopedic treatment of organic chemistry from an industrial, process research and development, and manufacturing point of view plenty of examples to illustrate the scope and limitation of the strategies a comprehensive index organised by topic, reaction type, and reagent an extensive literature survey. This is an essential and comprehensive guide for experienced practitioners of chemical process research and development, fresh recruits to chemical industry R&D divisions, and academics who are interested in interacting with the chemical industry, optimising their synthetic strategies, and enriching the field of atom economy.

Proceedings of 2nd European Organic Chemistry Congress 2017

Proceedings of 2nd European Organic Chemistry Congress 2017

Journal of Organic Chemistry: Current Research : Volume 6

  • Author: ConferenceSeries
  • Publisher: ConferenceSeries
  • ISBN: N.A
  • Category:
  • Page: 79
  • View: 8746
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May 11-13, 2017 Amsterdam, Nehterlands Key Topics : Elementary concepts of organic chemistry, Organometallic compounds, Bioorganic chemistry, Carbohydrates and phenols, Stereochemistry, Analytical techniques in organic chemistry, Carboxylic acids and its derivatives, Chemical bonding, Cheminformatics, Green and environmental chemistry, Polymers and monomers, Bio-chemistry and agricultural chemistry, Catalysis of organic reactions, Physical organic chemistry, Natural product chemistry,

Introduction to Green Chemistry

Introduction to Green Chemistry

  • Author: Albert Matlack
  • Publisher: CRC Press
  • ISBN: 9780849306235
  • Category: Science
  • Page: 568
  • View: 9132
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With roughly 5500 references, this book may be considered more of a treatise than a mere introduction to green chemistry. Using an unconventional approach, the author provides a broad but thorough review of the subject, covering traditional green chemistry topics such as catalysis, benign solvents, and alternative feedstocks before moving on to less frequently covered topics such as chemistry of longer wear and population and the environmental chemistry. Topics such as these highlight the importance of chemistry to everyday life and demonstrate the real benefits that wider exploitation of green chemistry can have for society.

Global Food Security and Supply

Global Food Security and Supply

  • Author: Wayne Martindale
  • Publisher: John Wiley & Sons
  • ISBN: 1118699297
  • Category: Technology & Engineering
  • Page: 232
  • View: 1112
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With the global population projected to reach 9 billion by theyear 2050, the need for nations to secure food supplies for theirpopulations has never been more pressing. Finding better supplychain solutions is an essential part of achieving a secure andsustainable diet for a rapidly increasing population. We are now ina position, through methods including life cycle assessment (LCA),carbon footprinting and other tools, to accurately measure andassess our use – or misuse – of natural resources,including food. The impact of new technologies and managementsystems can therefore improve efficiencies and find new ways toreduce waste. Global Food Security and Supply provides robust, succinctinformation for people who want to understand how the global foodsystem works. The book demonstrates the specific tools availablefor understanding how food supply works, addresses the challengesfacing a secure and safe global food supply, and helps readers toappreciate how these challenges might be overcome. This book is a concise and accessible text that focuses onrecent data and findings from a range of internationalcollaborations and studies. The author provides both asnapshot of global food supply and security today, and a projectionof where these issues may lead us in the future. This book willtherefore be of particular interest to food policy leaders,commercial managers in the food industry, and researchers andstudents seeking a better understanding of a rapidly evolvingtopic.

How Flavor Works

How Flavor Works

The Science of Taste and Aroma

  • Author: Nak-Eon Choi,Jung H. Han
  • Publisher: John Wiley & Sons
  • ISBN: 1118865456
  • Category: Technology & Engineering
  • Page: 240
  • View: 3059
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Taste is the number one driving force in the decision to purchase a food product and food consumption is the most critical function for living organisms to obtain the energy and resources essential to their vitality. Flavor and aroma are therefore universally important concepts: intrinsic to human well-being and pleasure, and of huge significance for the multi-trillion dollar global food business. How Flavor Works: the Science of Taste and Aroma offers a fascinating and accessible primer on the concepts of flavor science for all who have an interest in food and related topics. Professionals and students of food science and technology who do not already specialize in flavor science will find it a valuable reference on a topic crucial to how consumers perceive and enjoy food products. In this regard, it will also be of interest to product developers, marketers and food processors. Other readers with a professional (eg culinary and food service) or personal interest in food will also find the book interesting as it provides a user-friendly account of the mechanisms of flavor and aroma which will provide new insights into their craft.

The Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry

  • Author: Camille Georges Wermuth
  • Publisher: Elsevier
  • ISBN: 0080497772
  • Category: Science
  • Page: 736
  • View: 8576
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The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process. * The only book available dealing with the practical aspects of medicinal chemistry * Serves as a complete guide to the drug discovery process, from conception of the molecules to drug production * Updated chapters devoted to the discovery of new lead compounds, including combinatorial chemistry

Process Intensification

Process Intensification

Engineering for Efficiency, Sustainability and Flexibility

  • Author: David Reay,Colin Ramshaw,Adam Harvey
  • Publisher: Butterworth-Heinemann
  • ISBN: 0080983057
  • Category: Technology & Engineering
  • Page: 624
  • View: 6571
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Process Intensification: Engineering for Efficiency, Sustainability and Flexibility is the first book to provide a practical working guide to understanding process intensification (PI) and developing successful PI solutions and applications in chemical process, civil, environmental, energy, pharmaceutical, biological, and biochemical systems. Process intensification is a chemical and process design approach that leads to substantially smaller, cleaner, safer, and more energy efficient process technology. It improves process flexibility, product quality, speed to market and inherent safety, with a reduced environmental footprint. This book represents a valuable resource for engineers working with leading-edge process technologies, and those involved research and development of chemical, process, environmental, pharmaceutical, and bioscience systems. No other reference covers both the technology and application of PI, addressing fundamentals, industry applications, and including a development and implementation guide Covers hot and high growth topics, including emission prevention, sustainable design, and pinch analysis World-class authors: Colin Ramshaw pioneered PI at ICI and is widely credited as the father of the technology

Coating and Drying Defects

Coating and Drying Defects

Troubleshooting Operating Problems

  • Author: Edgar B. Gutoff,Edward D. Cohen
  • Publisher: John Wiley & Sons
  • ISBN: 0470044128
  • Category: Science
  • Page: 400
  • View: 1019
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A practical guide for ensuring a defect-free coating and drying process For professionals in the coating and drying industry, the world is a demanding place. New, technically complex products such as fuel cell membranes, thin film batteries, solar cells, and RFID chips require coatings of extreme precision. With the bar raised so high, understanding how to troubleshoot and eliminate defects on a coating line is an essential skill for all personnel. Coating and Drying Defects, Second Edition provides manufacturing and quality control personnel, equipment operators and supervisors, and plant engineers and scientists with the full complement of proven tools and techniques for detecting, defining, and eliminating coating defects and operating problems, and for ensuring that they do not recur. Updating the valuable contents of the first edition, this practical Second Edition: Describes all major processes for coating and drying of continuous film on sheets or webs Covers technologies that have been recently developed to prevent defect formation and improve operating procedures Provides a rational framework within which to assess and analyze virtually any defect that may arise Offers step-by-step guidelines for conducting every phase of the troubleshooting process, including defect prevention Going beyond simply describing a disparate set of troubleshooting techniques, this unique guide arms readers with a systematic, nonmathematical methodology encompassing the entire coating operation, becoming an indispensable resource for manufacturing and quality-control personnel as well as plant engineers, polymer scientists, surface scientists, organic chemists, and coating scientists.

Data mining

Data mining

praktische Werkzeuge und Techniken für das maschinelle Lernen

  • Author: Ian H. Witten,Eibe Frank
  • Publisher: N.A
  • ISBN: 9783446215337
  • Category:
  • Page: 386
  • View: 2163
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Organic Syntheses Based on Name Reactions

Organic Syntheses Based on Name Reactions

A Practical Guide to 750 Transformations

  • Author: Alfred Hassner,Irishi Namboothiri
  • Publisher: Elsevier
  • ISBN: 0080966314
  • Category: Science
  • Page: 612
  • View: 8019
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Organic Syntheses Based on Named Reactions is an indispensable reference companion for chemistry students and researchers. Building on Hassner & Stumer’s highly regarded 2e, this new work reviews 750 reactions, with over 100 new stereoselective and regioselective reactions. Each A-Z entry provides a carefully condensed summary of valuable information that a chemist needs to understand and utilize these fundamental reactions in their work, including brief practical details. The book is illustrated with real synthetic examples from the literature and about 3,400 references to the primary literature to aid further reading. Extensive indexes (name, reagent, reaction) and a very useful functional group transformation index help the reader fully navigate this extensive collection of important reactions. With its comprehensive coverage, superb organization and quality of presentation, this long-awaited new edition belongs on the shelf of every organic chemist. Handy reference guide that explains 750 established named processes and methods that are trusted and used by organic chemists to synthesize or transform molecules Provides key data on each transformation including background, mechanism and--uniquely to books in this area--experimental details Extensive and multiple indexes allow the reader to search for information as and how they want and to rapidly plan transformations

Practical Methods for Biocatalysis and Biotransformations 2

Practical Methods for Biocatalysis and Biotransformations 2

  • Author: John Whittall,Peter W. Sutton
  • Publisher: John Wiley & Sons
  • ISBN: 1118307860
  • Category: Technology & Engineering
  • Page: 368
  • View: 5010
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Biocatalysts are increasingly used by chemists engaged in finechemical synthesis within both industry and academia. Today, thereexists a huge choice of high-tech enzymes and whole cellbiocatalysts, which add enormously to the repertoire of syntheticpossibilities. Practical Methods for Biocatalysis and Biotransformations2 is a "how-to" guide that focuses on the practicalapplications of enzymes and strains of microorganisms that arereadily obtained or derived from culture collections. The sourcesof starting materials and reagents, hints, tips and safety advice(where appropriate) are given to ensure, as far as possible, thatthe procedures are reproducible. Comparisons to alternativemethodology are given and relevant references to the primaryliterature are cited. This second volume – which can be usedon its own or in combination with the first volume - concentrateson new applications and new enzyme families reported since thefirst volume. Contents include: introduction to recent developments and future needs inbiocatalysts and synthetic biology in industry reductive amination enoate reductases for reduction of electron deficientalkenes industrial carbonyl reduction regio- and stereo- selective hydroxylation oxidation of alcohols selective oxidation industrial hydrolases and related enzymes transferases for alkylation, glycosylation andphosphorylation C-C bond formation and decarboxylation halogenation/dehalogenation/heteroatom oxidation tandem and sequential multi-enzymatic syntheses Practical Methods for Biocatalysis and Biotransformations2 is an essential collection of biocatalytic methods forchemical synthesis which will find a place on the bookshelves ofsynthetic organic chemists, pharmaceutical chemists, and processR&D chemists in industry and academia.

The Publishers' Trade List Annual

The Publishers' Trade List Annual

  • Author: N.A
  • Publisher: N.A
  • ISBN: N.A
  • Category: American literature
  • Page: N.A
  • View: 3032
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Sigma-Aldrich Labware

Sigma-Aldrich Labware

  • Author: N.A
  • Publisher: N.A
  • ISBN: N.A
  • Category: Chemical apparatus
  • Page: N.A
  • View: 1074
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Chemical Engineering Progress

Chemical Engineering Progress

  • Author: N.A
  • Publisher: N.A
  • ISBN: N.A
  • Category: Chemical engineering
  • Page: N.A
  • View: 2079
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BPL News Bulletin

BPL News Bulletin

  • Author: Brooklyn Public Library
  • Publisher: N.A
  • ISBN: N.A
  • Category: Libraries
  • Page: N.A
  • View: 2723
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Bulletin of the Brooklyn Public Library

Bulletin of the Brooklyn Public Library

  • Author: Brooklyn Public Library
  • Publisher: N.A
  • ISBN: N.A
  • Category: Brooklyn (New York, N.Y.)
  • Page: N.A
  • View: 4967
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Electrospray and MALDI Mass Spectrometry

Electrospray and MALDI Mass Spectrometry

Fundamentals, Instrumentation, Practicalities, and Biological Applications

  • Author: Richard B. Cole
  • Publisher: John Wiley & Sons
  • ISBN: 1118211553
  • Category: Science
  • Page: 847
  • View: 9591
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Discover how advances in mass spectrometry are fueling newdiscoveries across a broad range of research areas Electrospray and MALDI Mass Spectrometry brings both veteranpractitioners and beginning scientists up to date with the mostrecent trends and findings in electrospray ionization andmatrix-assisted laser desorption/ionization (MALDI) massspectrometry. In particular, this Second Edition highlights howadvances in electrospray and MALDI mass spectrometry are supportingimportant discoveries in new and emerging fields such as proteomicsand metabolomics as well as in traditional areas of chemistry andphysics research. Electrospray AND MALDI Mass Spectrometry, SECOND EDITION isdivided into five parts: Part A, Fundamentals of ES, explains the fundamental phenomenaunderlying the electrospray process, including selectivity inionization and inherent electrochemistry, and concludes with achapter offering a comparative inventory of source hardware Part B, Fundamentals of MALDI, confronts ionization mechanisms,instrument development, and matrix selection, and includes a finalchapter that explores the special application of MALDI to obtaintwo-dimensional images of spatial distributions of compounds onsurfaces Part C, ES and MALDI Coupling to Mass SpectrometryInstrumentation, examines the coupling of these ionizationtechniques to various mass analyzers, including quadrupole iontrap, time-of-flight, Fourier transform ion cyclotron resonance,and ion mobility mass spectrometers Part D, Practical Aspects of ES and MALDI, investigatesanalytical issues including quantification, charge-statedistributions, noncovalent interactions in solution that arepreserved as gas-phase ions, and various means of ion excitation inpreparation for tandem mass spectrometry, and offers a guide to theinterpretation of even-electron mass spectra Part E, Biological Applications of ES and MALDI, examines therole of mass spectrometry in such areas as peptide and proteincharacterization, carbohydrate analysis, lipid analysis, and drugdiscovery Written by a team of leading experts, the book not only providesa critical review of the literature, but also presents key conceptsin tutorial fashion to help readers take full advantage of thelatest technological breakthroughs and applications. As a result,Electrospray and MALDI Mass Spectrometry will help researchersfully leverage the power of electrospray and MALDI massspectrometry. The judicious compartmentalization of chapters, andthe pedagogic presentation style throughout, render the book highlysuitable for use as a text for graduate-level courses in advancedmass spectrometry.