Search results for: advances-in-mitochondrial-medicine

Advances in Mitochondrial Medicine

Author : Roberto Scatena
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Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include all the clinical consequences of congenital or acquired mitochondrial dysfunctions. There are actually a growing number of studies which assign a significant pathogenic role to damaged mitochondria in different diseases: ischemia/reperfusion injury, neurodegenerative diseases, cancer with its dramatic sequelae (i.e, metastasis), metabolic syndrome, hyperlipidemias, just to mention a few of the most important pathologies. In this context, a further aspect that should not be disregarded is the interaction of pharmacological agents with mitochondria, not only in regard of the toxicological aspects but, above all, of the potential therapeutic applications. In fact, it is interesting to note that, while the properties of different so-called “mitoxicants” are well-known, the subtle linkages between drugs and mitochondria is still in need of a real pharmacological and therapeutic control at the clinical level. This lack of consideration can often lead to an underestimation of unwanted toxic effects but also of desirable therapeutic activities. A reevaluation of the potential clinical role of mitochondria could give a new light on some yet obscure aspects of human pathophysiology.

Recent Advances in Mitochondrial Medicine and Coenzyme Q10

Author : Ram B. Singh
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Recent Advances in Mitocondrial Medicine and Coenzyme Q10

Author : Anna Gvozdjáková
File Size : 31.6 MB
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Medical Marvels

Author : Eugene Straus
File Size : 46.61 MB
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Profiles one hundred individuals and discoveries that have changed the field of medicine throughout history.

Advances in Anti aging Medicine

Author : Ronald Klatz
File Size : 37.83 MB
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Ergebnisse der Inneren Medizin und Kinderheilkunde Advances in Internal Medicine and Pediatrics

Author : P. Frick
File Size : 25.83 MB
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Ergebnisse der Inneren Medizin und Kinderheilkunde Advances in Internal Medicine and Pediatrics

Author :
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In dieser Reihe werden abgeschlossene Teilgebiete der klinischen Forschung und experimentellen Medizin von Spezialisten erschöpfend dargestellt. Dabei werden biochemische, physiologische und pathologisch-anatomische Grundlagen, wenn erforderlich auch genetische epidemiologische Daten, berücksichtigt und bisherige Erkenntnisse mit neuesten Forschungsergebnissen in Zusammenhang gebracht.

Advances in Sports Medicine and Exercise Science

Author : American College of Sports Medicine
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Aging and Mitochondrial Efficiency in the Little Brown Bat Myotis Lucifugus

Author : Anja Karina Jasmin Brunet
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Current Advances in Genetics

Author :
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Mitochondria and Their Role in Cardiovascular Disease

Author : José Marín-García
File Size : 81.96 MB
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Over the past two decades, due to dramatic advances in molecular and cell biology, biochemistry, and genetics, our view on mitochondria as a relatively static cellular powerhouse has changed radically. We now know that these organelles play a critical role in the normal and in the damaged heart. Written by Dr. José Marín-García, Director of the Molecular Cardiology and Neuromuscular Institute, Mitochondria and Their Role in Cardiovascular Disease brings readers up- to-date on the many significant advances in the field of mitochondrial cardiovascular medicine. The book begins with a general introduction to mitochondria, followed by laboratory methods to study the structure and function of the organelle, regulation of replication and biogenesis, and the mechanisms and functional consequences of mitophagia and mitochondrial dynamics. Subsequent chapters deal with mitochondrial oxidative stress and the role that the organelle plays in cell signaling and cell death. Discussions will be undertaken on the biochemistry of mitochondrial cell signaling, including the nature of the proteins engaged in these processes, many of them only recently discovered. Later chapters examine the role of mitochondria and mitochondrial abnormalities in cardiovascular diseases, including their diagnosis, therapeutic options currently available, animal models of mitochondrial disease, and new frontiers in mitochondria cardiovascular medicine, including areas of research that are relatively new or developing, such as proteomics, next generation sequencing, and systems biology.

Taguchi Methods

Author : A. Bendell
File Size : 61.10 MB
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Twenty-three papers cover automotive, electronics, plastics, information technology, and process industries. Includes a critical view of future development. Among the contributions are four original translations from Japanese and French. No index. Annotation copyrighted by Book News, Inc., Portland, OR

The Ohio State University College of Veterinary Medicine Advances in Veterinary Medicine

Author : Ohio State University. College of Veterinary Medicine
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Nuclear Medicine and Biology Advances

Author : Claude Raynaud
File Size : 56.63 MB
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Advances in Mass Spectrometry in Biochemistry and Medicine

Author : Alberto Frigerio
File Size : 38.9 MB
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The relationship of vitamin E to cognition

Author : Patricia Ann Zrelak
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Advances in Material Design for Regenerative Medicine Drug Delivery and Targeting imaging

Author : V. Prasad Shastri
File Size : 38.2 MB
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Mitochondrial Disorders in Neurology 2

Author : Anthony Henry Vernon Schapira
File Size : 52.38 MB
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Gain practical explanations of the science underlying mitochondrial disorders in neurology. Written by leading experts, this new Blue Book helps you recognize and manage the diseases. Includes: Sections on the role of mitochondria in neurodegenerative disease The development of animal models for mitochondrial diseases The design of treatments for patients with mitochondrial defects

Recent Advances in Rehabilitation Medicine

Author : Olle Höök
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Annual Review of Genomics and Human Genetics

Author :
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