Search results for: an-introduction-to-protein-informatics

An Introduction to Protein Informatics

Author : Karl-Heinz Zimmermann
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Protein informatics is a newer name for an already existing discipline. It encompasses the techniques used in bioinformatics and molecular modeling that are related to proteins. While bioinformatics is mainly concerned with the collection, organization, and analysis of biological data, molecular modeling is devoted to representation and manipulation of the structure of proteins. Protein informatics requires substantial prerequisites on computer science, mathematics, and molecular biology. The approach chosen here, allows a direct and rapid grasp on the subject starting from basic knowledge of algorithm design, calculus, linear algebra, and probability theory. An Introduction to Protein Informatics, a professional monograph will provide the reader a comprehensive introduction to the field of protein informatics. The text emphasizes mathematical and computational methods to tackle the central problems of alignment, phylogenetic reconstruction, and prediction and sampling of protein structure. An Introduction to Protein Informatics is designed for a professional audience, composed of researchers and practitioners within bioinformatics, molecular modeling, algorithm design, optimization, and pattern recognition. This book is also suitable as a graduate-level text for students in computer science, mathematics, and biomedicine.

Proteome Informatics

Author : Conrad Bessant
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The field of proteomics has developed rapidly over the past decade nurturing the need for a detailed introduction to the various informatics topics that underpin the main liquid chromatography tandem mass spectrometry (LC-MS/MS) protocols used for protein identification and quantitation. Proteins are a key component of any biological system, and monitoring proteins using LC-MS/MS proteomics is becoming commonplace in a wide range of biological research areas. However, many researchers treat proteomics software tools as a black box, drawing conclusions from the output of such tools without considering the nuances and limitations of the algorithms on which such software is based. This book seeks to address this situation by bringing together world experts to provide clear explanations of the key algorithms, workflows and analysis frameworks, so that users of proteomics data can be confident that they are using appropriate tools in suitable ways.

Protein Bioinformatics

Author : Ingvar Eidhammer
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Pairwise global alignment of sequences. Pairwise local alignment and database search. Statical analysis. Multiple global alignment and phylogenetic trees. Scoring matrices. Profiles. Sequence patterns. Structures and structure descriptions. Superposition and Dynamic programming. Geometric techniques. Clustering: Combining local similarities. Significance and assessment of structure comparisons. Multiple structure comparison. Protein structure classification. Structure prediction: Threading. Basics in mathematics, probability and algorithms. Introduction to molecular biology.

Introduction to Clinical Informatics

Author : Patrice Degoulet
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Introduction to Clinical Informatics fills a void in the Computer in Health Care series. With this volume, Patrice Degoulet and Marius Fieschi provide a comprehensive view of medical informatics and carry that concept forward into the realm of clinical informatics. The authors draw upon their experi ences as medical school faculty members in France, where informatics has long been integrated into the curriculum and where the French version of this very book has been used, tested, and revised. In intent and content, this volume stands as the companion volume to Introduction to Nursing Informatics, one of the series' best selling titles. For practitioners and students of medicine, pharmacy, and other health profes sions, Introduction to Clinical Informatics offers an essential understanding how computing can support patient care, clarifying practical uses and critical issues. Today medical schools in the United States are making informatics a part of their curriculum, with required medical informatics blocks at the onset of training serving as the base for problem-based learning throughout the course of study. In an increasingly networked and computerized environ ment, health-care providers are having to alter how they practice. Whether in the office, the clinic, or the hospital, health-care professionals have access to a growing array of capabilities and tools as they deliver care. Learning to use these becomes a top priority, and this volume becomes a valuable resource.

Genome Informatics 2010 Genome Informatics Series Vol 24 Proceedings Of The 10th Annual International Workshop On Bioinformatics And Systems Biology Ibsb 2010

Author : Tatsuya Akutsu
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This volume contains 18 peer-reviewed papers based on the presentations at the 10th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2010) held at Kyoto University from July 26 to July 28, 2010. This workshop started in 2001 as an event for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following programs:Boston — Graduate Program in Bioinformatics, Boston University Berlin — The International Research Training Group (IRTG) “Genomics and Systems Biology of Molecular Networks”Kyoto — The JSPS International Training Program (ITP) “International Research and Training Program of Bioinformatics and Systems Biology”Tokyo — Global COE Program “Center of Education and Research for Advanced Genome-Based Medicine”/a

Genome Informatics 2010

Author : Tatsuya Akutsu
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This volume contains 18 peer-reviewed papers based on the presentations at the 10th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2010) held at Kyoto University from July 26 to July 28, 2010. This workshop started in 2001 as an event for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following programs: bull; Boston - Graduate Program in Bioinformatics, Boston University bull; Berlin - The International Research Training Group (IRTG) "Genomics and Systems Biology of Molecular Networks" bull; Kyoto - The JSPS International Training Program (ITP) "International Research and Training Program of Bioinformatics and Systems Biology" bull; Tokyo - Global COE Program "Center of Education and Research for Advanced Genome-Based Medicine"

Information Technology in Bio and Medical Informatics

Author : M. Elena Renda
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This book constitutes the refereed proceedings of the 6th International Conference on Information Technology in Bio- and Medical Informatics, ITBAM 2015, held in Valencia, Spain, in September 2015, in conjunction with DEXA 2015. The 9 revised long papers presented together with 1 poster paper were carefully reviewed and selected from 15 submissions. The papers address the following two topics: medical terminology and clinical processes and machine learning in biomedicine.

Methods and Results in Crystallization of Membrane Proteins

Author : So Iwata
File Size : 79.46 MB
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Biomedical Informatics in Translational Research

Author : Hai Hu
File Size : 85.50 MB
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This trailblazing resource on biomedical informatics provides medical researchers with innovative techniques for integrating and federating data from clinical and molecular studies. This volume helps researchers manage data, expedite their efforts, and make the most of targeted basic research.

Bio Informatics

Author : Sangita
File Size : 78.48 MB
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Informatics In Proteomics

Author : Sudhir Srivastava
File Size : 77.80 MB
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The handling and analysis of data generated by proteomics investigations represent a challenge for computer scientists, biostatisticians, and biologists to develop tools for storing, retrieving, visualizing, and analyzing genomic data. Informatics in Proteomics examines the ongoing advances in the application of bioinformatics to proteomics research and analysis. Through computer simulations, scientists can determine more about how diseases affect cells, predict how various drug interventions would work, and ultimately use proteins as therapeutic targets. This book first addresses the infrastructure needed for public protein databases. It discusses information management systems and user interfaces for storage, retrieval, and visualization of the data as well as issues surrounding data standardization and integration of protein sequences recorded in the last two decades. The authors subsequently examine the application of statistical and bioinformatic tools to data analysis, data presentation, and data mining. They discuss the implementation of algorithms, statistical methods, and computer applications that facilitate pattern recognition and biomarker discovery by integrating data from multiple sources. This book offers a well-rounded resource of informatic approaches to data storage, retrieval, and protein analysis as well as application-specific bioinformatic tools that can be used in disease detection, diagnosis, and treatment. Informatics in Proteomics captures the current state-of-the-art and provides a valuable foundation for future directions.

An Introduction to Chemoinformatics

Author : Andrew R. Leach
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This book aims to provide an introduction to the major techniques of chemoinformatics. It is the first text written specifically for this field. The first part of the book deals with the representation of 2D and 3D molecular structures, the calculation of molecular descriptors and the construction of mathematical models. The second part describes other important topics including molecular similarity and diversity, the analysis of large data sets, virtual screening, and library design. Simple illustrative examples are used throughout to illustrate key concepts, supplemented with case studies from the literature.

Computational Intelligence in Medical Informatics

Author : Arpad Kelemen
File Size : 88.80 MB
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Medical Informatics (MI) is an emerging interdisciplinary science. This book deals with the application of computational intelligence in MI. Addressing the various issues of medical informatics using different computational intelligence approaches is the novelty of this edited volume. This volume comprises of 15 chapters selected on the basis of fundamental ideas/concepts including an introductory chapter giving the fundamental definitions and some important research challenges.

Computational Intelligence and Pattern Analysis in Biology Informatics

Author : Ujjwal Maulik
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An invaluable tool in Bioinformatics, this unique volume provides both theoretical and experimental results, and describes basic principles of computational intelligence and pattern analysis while deepening the reader's understanding of the ways in which these principles can be used for analyzing biological data in an efficient manner. This book synthesizes current research in the integration of computational intelligence and pattern analysis techniques, either individually or in a hybridized manner. The purpose is to analyze biological data and enable extraction of more meaningful information and insight from it. Biological data for analysis include sequence data, secondary and tertiary structure data, and microarray data. These data types are complex and advanced methods are required, including the use of domain-specific knowledge for reducing search space, dealing with uncertainty, partial truth and imprecision, efficient linear and/or sub-linear scalability, incremental approaches to knowledge discovery, and increased level and intelligence of interactivity with human experts and decision makers Chapters authored by leading researchers in CI in biology informatics. Covers highly relevant topics: rational drug design; analysis of microRNAs and their involvement in human diseases. Supplementary material included: program code and relevant data sets correspond to chapters.

Genome Informatics 2009

Author : Charles DeLisi
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This volume contains 17 peer-reviewed papers based on the presentations at the 9th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2009) held at the Life Science Engineering Building of Boston University from July 27 to 29, 2009. This workshop started in 2001 as a platform for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following institutions and programs: * Boston University Graduate Program in Bioinformatics * Charit Universittsmedizin Berlin * Freie Universitt Berlin * Global COE Program Center of Education and Research for Advanced Genome-Based Medicine, University of Tokyo * The International Research Training Group (IRTG) Genomics and Systems Biology of Molecular Networks * International Research and Training Program on Bioinformatics and Systems Biology, Kyoto University Bioinformatics Center * Max-Delbrck Center for Molecular Medicine in Berlin * Max Planck Institute for Molecular Genetics in Berlin * Max Planck Institute of Molecular Plant Physiology in Potsdam

Biocomputation and Biomedical Informatics Case Studies and Applications

Author : Lazakidou, Athina A.
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"This book provides a compendium of terms, definitions, and explanations of concepts, processes, and acronyms"--Provided by publisher.

Biomacromolecules

Author : C. Stan Tsai
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This book provides an integrated treatment of the structure and function of nucleic acids, proteins, and glycans, including thorough coverage of relevant computational biochemistry. The text begins with an introduction to the biomacromolecules, followed by discussion of methods of isolation and purification, physiochemical and biochemical properties, and structural characteristics. The next section of the book deals with sequence analysis, analysis of conformation using spectroscopy, chemical synthesis, and computational approaches. The following chapters discuss biomolecular interactions, enzyme action, gene transmission, signal transduction, and biomacromolecular informatics. The author concludes with presenting the latest findings in genomics, proteomics, glycomics, and biomacromolecular evolution. This text is an invaluable resource for research professionals wishing to move into genomics, proteomics, and glycomics research. It is also useful for students in biochemistry, molecular biology, bioengineering, biotechnology, and bioinformatics.

Biomedical Signals Imaging and Informatics

Author : Joseph D. Bronzino
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Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Biomedical Signals, Imaging, and Informatics, the third v

Information Technology in Bio and Medical Informatics ITBAM 2010

Author : Sami Khuri
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This book constitutes the thoroughly refereed proceedings of the First International Conference on InformationTechnology in Bio- and Medical Informatics, held in Bilbao, Spain, in September 2010. The 14 selected long papers and 8 selected short papers are divided in the following groups:Workflow management and database; Decision support and data management in biomedicine; Medical data modelling and information retrieval; Data mining in bioinformatics; Knowledge representation and data management in bioinformatics; Biological data and signal processing.

Introduction to Bioinformatics

Author : Arthur Lesk
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Lesk provides an accessible and thorough introduction to a subject which is becoming a fundamental part of biological science today. The text generates an understanding of the biological background of bioinformatics.