Search results for: clinical-mr-spectroscopy

Clinical MR Spectroscopy

Author : Peter B. Barker
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Covers all MR spectroscopy techniques and their clinical applications in neurological disorders, malignancies and musculoskeletal diseases.

MR Spectroscopy of the Brain

Author : Lara Alexandre Brandão
File Size : 46.26 MB
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This volume is a practical guide to the technique and most frequent clinical applications of magnetic resonance spectroscopy (MRS) of the brain. Using more than 500 images, the authors present the fundamentals of MRS in a straightforward fashion and show radiologists and neurologists how to recognize normal and disease processes on scans. The book presents the spectra of the most common neurological disease entities, along with the conventional images and perfusion and diffusion where appropriate. The authors thoroughly describe the pathology and key MRS features of each disease process. Each chapter ends with a quick-reference summary of the main findings.

Clinical MR Neuroimaging

Author : Jonathan H. Gillard
File Size : 34.92 MB
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Covers each physiological MR methodology and their applications to all major neurological diseases.

MR Spectroscopy of Pediatric Brain Disorders

Author : Stefan Blüml
File Size : 20.21 MB
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Magnetic resonance spectroscopy (MRS) is a modality available on most clinical MR scanners and readily integrated with standard MR imaging (MRI). For the brain in particular, MRS has been a powerful research tool providing additional clinically relevant information for several disease families such as brain tumors, metabolic disorders, and systemic diseases. The most widely-available MRS method, proton (1H; hydrogen) spectroscopy, is FDA approved for general use in the US and can be ordered by clinicians for patient studies if indicated. There are several books available that describe applications of MRS in adults. However, to the best of our knowledge there is currently no book available that focuses exclusively on applications in pediatrics. MR spectroscopy in the pediatric population is different from adults for two main reasons. Particularly in the newborn phase the brain undergoes biochemical maturation with dramatic changes of the "normal" biochemical fingerprint. Secondly, brain diseases in the pediatric population are different from adult disorders. For example, brain tumors, which are mostly gliomas in the adults, often originate from different cell types and are also more diverse even within the same type and grade of tumor. This diversity of diseases and its implications for MR spectroscopy has not been addressed sufficiently in the literature, we believe. The target audience for "MR Spectroscopy of Pediatric Brain Disorders" are thus both clinicians and researchers involved with pediatric brain disorders. This includes radiologists, neurologists, neurooncologists, neurosurgeons, and more broadly the neuroscience and neurobiology community. This book will provide the necessary background information to understand the basics of MR spectroscopy. This will be followed by a detailed discussion of the normal biochemical maturation which will highlight the metabolic differences between the pediatric and adult brain. Thereafter, in SECTION I individual chapters will address various pediatric brain disease families. Of particular importance for pediatrics are case studies. For that reason, SECTION II will contain a large number of case studies. This will be particularly important for clinicians who may want to see examples of MRS for various conditions. A standardized format will be used for case reports that allow the reader to quickly understand the history of each case presented and the significance of the findings. The case reports will also include information from other imaging modalities to point out any added value of MRS in addition to conventional studies and clinical information. This section is necessary because the format of providing more complete information about individual patients is not practical for the chapters in SECTION I.

Clinical MR Neuroimaging

Author : Jonathan H. Gillard
File Size : 58.9 MB
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The physiological magnetic resonance techniques of diffusion imaging, perfusion imaging and spectroscopy offer insights into brain structure, function and metabolism. Until recently, they were mainly applied within the realm of medical research, but with their increasing availability on clinical MRI machines, they are now coming into clinical practice for the evaluation of neuropathology in individual patients. This book provides the reader with a thorough review of the underlying physical principles of each of these methods, as well as comprehensive coverage of their clinical applications. Topics covered include single- and multiple-voxel MRS techniques, MR perfusion based on both arterial spin labelling and dynamic bolus tracking approaches, and diffusion-weighted imaging, including techniques for mapping brain white matter fiber bundles. Clinical applications are reviewed in depth for each technique, with case reports included throughout the book. Attention is also drawn to possible artifacts and pitfalls associated with these techniques.

Clinical MR Neuroimaging

Author : Jonathan H. Gillard
File Size : 78.39 MB
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Clinical MR Neuroimaging, second edition, provides radiologists, neuroscientists and researchers with a clear understanding of each physiological MR methodology and their applications to the major neurological diseases. Section 1 describes the physical principles underlying each technique and their associated artefacts and pitfalls. Subsequent sections review the application of MRI in a range of clinical disorders: cerebrovascular disease, neoplasia, infection/inflammation/demyelination disorders, seizures, psychiatric/neurodegenerative conditions, and trauma. This new edition includes all recent advances and applications, with greatly increased coverage of permeability imaging, susceptibility imaging, iron imaging, MR spectroscopy and fMRI. All illustrations are completely new, taking advantage of the latest scan capabilities to give images of the highest possible quality. In addition, over 35 new case studies have been included. Editors and contributors are the leading neuroimaging experts worldwide; their unique combination of technical knowledge and clinical expertise makes Clinical MR Neuroimaging the leading text on the subject.

Handbook of Magnetic Resonance Spectroscopy In Vivo

Author : Paul A. Bottomley
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This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients. Comprised of three parts: Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring. Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity. Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit the eMagRes Homepage


Author : Mark A. Brown
File Size : 48.32 MB
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MRI Basic Principles and Applications Second Edition Mark A. Brown, PhD and Richard C. Semelka, MD This updated edition provides a bridge between the theory of magnetic resonance imaging (MRI) and its implementation in commercial scanners. As with its popular predecessor, MRI: Basic Principles and Applications, Second Edition integrates a clear discussion of the basic physics of MRI, including resonance absorption, relaxation, and pulse sequences, with an overview of the guiding principles of its clinical application (such as motion artifact reduction and fat suppression techniques). With over 80 images and numerous line drawings illustrating and clarifying key concepts and applications, MRI: Basic Principles and Applications, Second Edition remains an essential introductory text for radiologists, technologists, and radiology residents. From reviews of the First Edition "This book is well written and presents difficult concepts in an understandable fashion. It makes it easy for those with science backgrounds to understand clinical MR applications and for clinicians to understand the basics of MR physics." -Radiation Research Related Titles Clinical MR Spectroscopy: First Principles Nouha Salibi, PhD and Mark A. Brown, PhD Acquaints readers with the basic concepts of MR spectroscopy and provides guidelines for its clinical use PACS: Basic Principles and Applications H. K. Huang, DSc Integrates a comprehensive introduction to the imaging modalities and technical fundamentals of "filmless radiology" with guidelines for designing and implementing a PACS system


Author : A. Haase
File Size : 46.58 MB
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In this Syllabus, the reader will find crutial information on MR methodology, clinical aspects of MR imaging, and MR spectroscopy. In particular, the relevant MR equipment specifications, efficacy and cost-effectiveness considerations, set-up and potentials of various imaging contrasts and spectroscopy applications will be covered. A special section will focus on the effects of patient ageing.

Clinical MR Spectroscopy

Author : Nouha Salibi
File Size : 77.60 MB
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Magnetic resonance spectroscopy (MRS) has been an important analytical tool in organic chemistry, biology, and materials science for more than a half-century. Now, recent advances in the clinical application of MRS are allowing radiologists to more effectively diagnose lymphoma, head and neck cancers, and brain tumors, as well as to understand metabolic brain anomalies such as stroke and dementia. Clinical MR Spectroscopy: First Principles acquaints readers with the basic physics and chemistry of MRS while providing clear, practical guidelines for its clinical use. While most readers are likely to have had experience with MRI, this is not a prerequisite for understanding either the basic science or applied sections of the book. Individual chapters address such topics as: * The basic concepts of MRS * Hardware and software requirements * Techniques for localized spectroscopy * Spectroscopy data processing * The application of MRS in examining the brain, heart, muscles, and liver. Clinical MR Spectroscopy: First Principles features numerous line drawings to clarify the basic science of MRS and images to illustrate its clinical utility. This concise and timely book provides an accessible but comprehensive resource for radiologists, MRI technologists, and radiology residents.