Search results for: new-trends-in-gastric-cancer

New Trends in Gastric Cancer

Author : P.I. Reed
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Despite the fact that the incidence of gastric cancer is declining in the Western world, it remains a significant problem with respect to accurate diagnosis and treatment since it has a high mortality rate. In June 1989 an International Conference was held at the University of Rome "La Sapienza" entitled "New Trends in Gastric Cancer: Background and videosurgery". During this meeting background information on the aetiopathogenesis of gastric cancer was presented together with talks and video presentations on the latest advances in the treatment of gastric carcinoma, both from the European and Japanese experience. Because of the poor prognosis of gastric carcinoma there is increasing pressure for early detection. Some of the problems in the early detection of gastric carcinoma are discussed together with methods of surveillance of high-risk subjects. It is generally accepted that the surgical approach to gastric carcinoma should take into account the site and extent of the lesion and there are chapters on new methods for pre and intraoperative staging of the disease which allow a more logical approach to surgery. A comparison between Japanese and Western rule and results was attempted and reasons for the differences were investigated. Since the field is still evolving not all aspects could be covered, and those angles not approached in this book will be addressed in a second International Conference to be held in Rome in June 1990.

New Developments in the Management of Gastric Cancer

Author : P. Malfertheiner
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The overall prognosis for patients with gastric cancer remains poor as tumors are often diagnosed at an advanced stage, despite new developments and technical advances in endoscopic diagnosis and therapy. This publication brings together leading experts in the fields of basic research and clinical management of gastric cancer, to share their expertise with the clinical community. State-of-the-art reviews discuss the pathogenesis of and the most important risk factors for the development of gastric cancer, potential benefits of chemoprevention and Helicobacter pylori eradication. Moreover, new diagnostic modalities and surgical therapy, including the potential benefits of neoadjuvant and adjuvant therapies, are presented. As most patients require palliative therapy because of locally advanced or metastasized cancers, several reviews are dedicated to advances in the chemotherapy of advanced gastric cancers and peritoneal metastasis. Finally, future approaches towards a molecular diagnosis and therapy are described. Those involved in the management of gastric cancer patients will find the information presented in this publication of utmost help and will benefit greatly for their daily routine.

Gastric Cancer Research Trends

Author : Marilyn B. Tompkins
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Stomach cancer (also called gastric cancer) is the growth of cancer cells in the lining and wall of the stomach. Stomach cancer represents roughly 2 percent (25,500) cases of all new cancer cases yearly in the United States, but it is much more common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low intake of fruits and vegetables.Infection with H. pylori is the main risk factor in about 80 percent or more of gastric cancers. It is more common in men. A very small percentage of diffuse-type gastric cancers are thought to be genetic. Hereditary Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment options are available for families at risk. Metastasis occurs in 80-90 percent of individuals with stomach cancer, with a five year survival rate of 75 percent in those diagnosed in early stages and less than 30 percent of those diagnosed in late stages. This book presents new and important research from around the world.

Lynch Syndrome New Insights for the Healthcare Professional 2011 Edition

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Lynch Syndrome: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Lynch Syndrome in a compact format. The editors have built Lynch Syndrome: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Lynch Syndrome in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Lynch Syndrome: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at

Surgery for Gastric Cancer

Author : Sung Hoon Noh
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This book clearly describes the surgical procedures employed in patients with gastric cancer. The techniques used in the various types of gastrectomy are presented step by step, and the roles of endoscopic treatment and chemotherapy are also discussed. A distinctive practical feature is the provision of accompanying online videos of standard surgical procedures, which will serve as excellent learning aids for novice practitioners and provide ideal teaching material for experienced surgeons. Surgery remains the mainstay in the treatment of gastric cancer. With advances in tumor biology and technical developments, gastric cancer surgery has become more diverse and its outcomes have steadily improved. However, further improvement of certain aspects of surgical procedures and techniques is still required. Surgery for Gastric Cancer will acquaint readers with the state of the art in the field and prove a valuable tool in the quest for optimal practice.

New Trends in Cancer for the 21st Century

Author : Antonio Llombart-Bosch
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This volume contains the lectures held at the International Symposium on Cancer "New Trends in Cancer for the 21st Century". Fundamental researchers, politicians and representatives from patient coalitions share their knowledge and interests as well as their concerns and experiences. Not only do these papers provide state-of-the-art information on cancer, they are also an opportunity to look at the problem from different points of view.

Cancer of the Upper Gastrointestinal Tract

Author : Mitchell C. Posner
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Collectively, cancer of the esophagus, stomach and small intestine represent the second most common site and cause of death amongst the digestive system cancers. These disparate malignancies have one thing in common: consistently effective treatment remains elusive. This book is a comprehensive guide to diagnosis, management, and post-treatment care. Epidemiologic factors, molecular and biologic determinants, diagnostic/staging methods and treatment modalities are described for each organ site. The text is thoroughly supported by color illustrations, a key feature of the American Cancer Society Atlas of Clinical Oncology series. The expert contributors from medical, surgical and radiation oncology examine the advances in imaging, interventional gastroenterology, surgical technique, and combined modality therapy and discuss their impact in the management of this challenging group of cancers.

Evidence based Surgery

Author : Toby A. Gordon
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As the healthcare environment changes, the need for outcomes-based tre atment planning becomes even more critical. This book guides the reade r through current outcomes-based research as it pertains to surgery. F irst, it gives a complete overview of the practice of evidence-based s urgery (EBS), with topics such as treatment planning, policy issues, a nd ethical issues. Then it gives practical, step-by-step advice on the methodology of EBS, with chapters on study design, outcomes measures, adjustments for complications and comorbidities, cost, and data sourc es. Last, it publishes the results of numerous respected EBS studies.

Women at High Risk to Breast Cancer

Author : B.A. Stoll
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A reprint of the 1989 edition of this book has been made necessary by continuing demand after rapid exhaustion of the first printing. In the two years since its appearance, there has been relatively little expansion of knowledge on this topic, and its massive accumulation of references still remains an authoritative guide in the difficult task of developing a national breast cancer prevention model. At the same time, its thesis has been sharpened by the publication of a companion volume Approaches to Breast Cancer Prevention (Kluwer, 1991) similarly edited byrne. Breast cancer is on the increase throughout the Western world where it is a major source of anxiety among women. The disease is also becoming more frequent in Asian and South American countries where once it was relatively uncommon. Multiple fac tors are suspected of promoting the disease and the increasing risk is attributed to recent changes in life-style and diet. This book is intended to provide an authorita tive and balanced survey of the latest research into the genetic, familial, hormonal, reproductive, nutritional, social and geographic factors known to be associated with an increased predisposition to the disease.

Gastric Cancer

Author : Takashi Sugimura
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The editors have produced a concise and up-to-date account of all aspects of gastric cancer, which is still one of the five major causes of cancer death in most countries of the world today. The book ranges from epidemiology, aetiology, and biology, to surgical and non-surgical treatements andprimary and secondary prevention. It summarizes the latest progress in the various fields, as well as providing practical guidance on diagnosis and management, and is written by acknowledged experts in the subject both in the West and Japan.

Issues in National Regional and Environmental Health and Medicine 2011 Edition

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Issues in National, Regional, and Environmental Health and Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about National, Regional, and Environmental Health and Medicine. The editors have built Issues in National, Regional, and Environmental Health and Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about National, Regional, and Environmental Health and Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in National, Regional, and Environmental Health and Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at

Total Gastrectomy in Gastric Carcinoma

Author : Thomas Zilling
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Rough Sets and Current Trends in Computing

Author : Pa.) Rsctc 200 (2002 Malvern
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This book constitutes the refereed proceedings of the Third International Conference on Rough Sets and Current Trends in Computing, RSCTC 2002, held in Malvern, PA, USA in October 2002. The 76 revised regular papers and short communications presented together with 2 keynotes and 5 plenary papers were carefully reviewed and selected from more than 100 submissions. The book offers topical sections on foundation and methods; granular and neural computing; probabilistic reasoning; data mining, machine learning and pattern recognition; Web mining; and applications.

Epidemiology of Cancer of the Digestive Tract

Author : Pelayo Correa
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The digestive organs are the most frequent site of cancer in the world, accounting for approximately 30% of all malignant tumors. This prominent position has been present for many decades in spite of marked shifts in the freq uency of cancer of specific organs. The most remarkable shift has been the decrease in gastric cancer rates occurring concomitantly with an increase in colon cancer rates in most 'western' industrialized societies. Important exceptions to this rule, as well as other epidemiologic evidence, indicate that the opposite trends for gastric and colon cancers are not inevitable consequences of each other. Although genetic ally determined precancerous syndromes are well recognized, it is generally agreed that environmental factors play an overriding role in digestive cancer causation. The most obvious environmental factors seem to be the result of what we eat, drink, or smoke. Although the nutritional component of the diet is of unquestionable importance, the nonnutrient elements in our diet have also proven to be influential causative factors. Several studies have focused on the microenvironment at the level of the mucosa or the digestive organs as a micro cosmos where forces promoting and inhibiting carcinogenesis are operating for a prolonged period of time. Their interaction eventually determines the presence or absence of a malignant tumor. Our understanding of such modulating forces, hopefully, will someday allow us to modify the microenvironment in a favorable way and attain the goal of cancer prevention.

Surgery in the Multimodal Management of Gastric Cancer

Author : Giovanni De Manzoni
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Although there has been a slow but steady decrease in incidence, gastric cancer remains the second leading cause of cancer death worldwide. Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and oncological treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on the different open and minimally invasive surgical techniques and discussing intraoperative chemohyperthermia and neoadjuvant and adjuvant treatment. Operative endoscopy and endoscopic ultrasonography are also discussed, as these now have an important role in both diagnostic work-up and palliative care of gastric cancer patients. Only a multidisciplinary approach involving the surgeon, gastroenterologist, and oncologist can produce the comprehensive and integrated overview that today constitutes a winning strategy for the optimization of results.What we hope we have achieved is a flexible, up-to-date, exhaustive publication, rich in illustrations and consistent with evidence-based medicine.

Management of Gastric Cancer

Author : Paul H. Sugarbaker
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Gastric cancer has been one of the great malignant scourges affecting man kind for as long as medical records have been kept. Until operative resection pioneered by Bilroth and others became available, no effective treatment was feasible and death from cancer was virtually inevitable. Even with resection by total gastrectomy, the chances of tumor eradication remained small. Over recent years, however, the situation has been changing. Some changes have resulted from better understanding of the disease, early detec tion, and better management techniques with applied clinical research, but the reasons for other changes are poorly understood. For example, the incidence of gastric cancer is decreasing, especially in westernized societies, where it has fallen from one of the most common cancers to no longer being in the top five causes of cancer death. Still it remains the number one killer of adult males in Japan and Korea. Whether the reduced incidence in western societies is a result of dietary changes or methods of food preservation, or some other reason, is as yet uncertain. Improvements in outcome have been reported from mass screening and early detection; more refined techniques of establishing early diagnosis, tumor type, and tumor extent; more radical surgical resection; and resection at earlier stages of disease.

Understanding Pancreatic Cancer Current Trends ECAB

Author : Markus W Büchler
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Pancreatic cancer remains a dismal disease with an incidence that is on the rise even in a low incidence region like India. In recent years, there have been significant advances in the understanding of pancreatic cancer largely due to strides in modern molecular biology, pathology and radiology. While molecular biology continues to provide an optimistic vision for future treatment approaches to this deadly disease, the recent identification of PanIN’s and resection margins in pancreatic cancer have important implications for current day-to-day practice. This book explains how better understanding of IPMN and its management has improved the scope of pancreatic tumors. It also explains what role do heat shock proteins perform in cancer. The book gives concise description on how a number of important advances have made pancreatic pathology an exciting and rapidly advancing field. There are chapters that explain how good endoscopic ultrasound is in detection of cancer pancreas and also talk about experimental studies on obstructive jaundice and biliary drainage. Neo-adjuvant strategies in operable pancreatic adenocarcinomas are also being explained in detail. It is sincerely hoped that this book will update the busy clinician as well as the academician on various aspects of current importance in management of pancreatic cancer. Understanding the role of IPMN in improving the scope of pancreatic tumors Describing performance of heat shock proteins in cancer Throwing some light on usefulness of endoscopic ultrasound in detecting cancer pancreas Getting an insight into neo-adjuvant strategies in operable pancreatic adenocarcinomas

Familial Cancer Control

Author : Walter Weber
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The European School of Oncology came into existence to respond to a need for informa tion, education and training in the field of the diagnosis and treatment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidisciplinary approach which is difficult for the Univer sities to put into practice since their system is mainly disciplinary orientated. Secondly, the rate of technological development that impinges on the diagnosis and treatment of cancer has been so rapid that it is not an easy task for medical faculties to adapt their curricula flexibly. With its residential courses for organ pathologies and the seminars on new techniques (laser, monoclonal antibodies, imaging techniques etc.) or on the principal therapeutic controversies (conservative or mutilating surgery, primary or adjuvant chemotherapy, radiotherapy alone or integrated), it is the ambition of the European School of Oncology to fill a cultural and scientific gap and, thereby, create a bridge between the University and Industry and between these two and daily medical practice. One of the more recent initiatives of ESO has been the institution of permanent study groups, also called task forces, where a limited number of leading experts are invited to meet once a year with the aim of defining the state of the art and possibly reaching a consensus on future developments in specific fields of oncology.

Cancer Forum

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Gastric Cancer

Author : C. Herfarth
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The problem of gastric cancer, with its multifaceted aspects, offers an example of diversified oncological research, which includes epidemiology, pathogenesis, histo morphology, surgical and conservative therapy in its spectrum. This disease not only constitutes an interesting and important subject for research, but it is also a challenge for the practitioner due to its inordinately poor prognosis. It therefore appeared a rewarding task to the editors to collect information from individual experts, in order to gain a topical summary of the problems pertaining to gastric cancer, as well as to provide a survey of the progress and the therapeutic possibilities in this field. This task was particularly enticing, as gastric cancer has lately come to belong to those tumors somewhat relegated to the shadows, although it is, despite its decreased fre quency in some western countries, still one of the most prevalent malignant diseases. This collection should emphasize the need for broadly based knowledge of individual problems as a prerequisite for any satisfactory therapy of an organ tumor. It is therefore the primary concern of this book to furnish anyone with an interest in oncology with this necessary survey. The editors thank Mrs. Karin Dohmeier and Mrs. Karin Kluge from Springer-Verlag for their cooperation in preparing this monograph. We extend our thanks to Mrs. Susanne Schenk and Mrs. Marga Wild, who contributed so much by her secretarial experience for the success of this volume. lJIm,September1979 Ch. Herfarth P. Schlag Table of Contents 1 Epidemiology and Pathogenesis . . . . . . . . . . .