Search results for: oral-tolerance

Oral Tolerance

Author : Olivier Morteau
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Oral tolerance is a major immunological property of the gastrointestinal mucosa. It plays a critical role in immune defence by preventing inflammatory and allergic responses to dietary and non pathogenic microbial antigens. The interest in oral tolerance has been renewed in the recent years, due to novel insights on its cellular mechanisms and potential clinical applications in the treatment of autoimmune diseases. Oral Tolerance: Cellular and Molecular Basis, Clinical Aspects, and Therapeutic Potential, has been designed as a concise yet comprehensive overview of the newest fundamental and clinical advances in the field. Based on the outstanding contribution of world experts, this book will be helpful to students, clinicians, and researchers working in mucosal immunology and gastroenterology. The first part of this volume describes the structure and functions of the gastrointestinal mucosa and the fundamental features and mechanisms of oral tolerance, including the role of T cells, cytokines, IgA antibodies, and bacterial antigens. The second part explores the clinical implications of the disruption of oral tolerance in Inflammatory Bowel Diseases, food and milk allergies, and coeliac disease in particular. The final chapter focuses on the clinical potential of oral tolerance as a promising therapeutic tool.

Fundamental Immunology

Author : William E. Paul
File Size : 68.11 MB
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Now thoroughly revised and updated, this comprehensive, up-to-date text is ideal for graduate students, post-doctoral fellows, microbiologists, infectious disease physicians, and any physician who treats diseases in which immunologic mechanisms play a role.

GI Microbiota and Regulation of the Immune System

Author : Gary B. Huffnagle
File Size : 31.81 MB
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This book covers current trends in the investigation of GI microbiota. It examines the relationship between the microbiota and the immune system from a variety of angles.

Design Principles for the Immune System and Other Distributed Autonomous Systems

Author : Lee A. Segel
File Size : 72.11 MB
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Design Principles for the Immune System and Other Distributed Autonomous Systems is the first book to examine the inner workings of such a variety of distributed autonomous systems--from insect colonies to high level computer programs to the immune system. It offers insight into the fascinating world of these systems that emerge from the interactions of seemingly autonomous components and brings us up-to-date on the state of research in these areas. Using the immune system and certain aspects of its functions as a primary model, this book examines many of the most interesting and troubling questions posed by complex systems. How do systems choose the right set of agents to perform appropriate actions with appropriate intensities at appropriate times? How in the immune system, ant colonies and metabolic networks does the diffusion and binding of a large variety of chemicals to their receptors permit coordination of system action? What advantages drive the various systems to complexity, and by what mechanisms do the systems cope with the tendency toward unwieldiness and randomness of large complex systems?

Oral Tolerance

Author : Howard L. Weiner
File Size : 68.88 MB
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Presents papers and poster abstracts from the spring 1995 title conference held in New York City, detailing mechanisms of oral tolerance and immune regulation. Sections on anatomy and physiology; mechanisms of oral tolerance; modulation of oral tolerance; and human and animal models of oral toleranc

DNA Vaccines

Author : Hildegund C. J. Ertl
File Size : 85.82 MB
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Feeding During Late Infancy and Early Childhood

Author : Olle Hernell
File Size : 71.89 MB
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In its resolution WHA54.2 (2001) the WHO recommends the promotion and support of exclusive breastfeeding for 6 months, and then the provision of safe and appropriate complementary foods whilst continuing breastfeeding until 2 years of age or beyond. The 56 Nutrition Workshop has been specifically developed to review the medical and scientific aspects of these topics and to sustain the Nestle Development Nutrition Program (NDNP).

Adverse Reactions to Food

Author : Dr. Judy Buttriss
File Size : 35.66 MB
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Continuing the exciting series of BNF Task Force Reports, Adverse Reactions to Foods covers in depth food allergy, food intolerance, nutrition and the immune system and autoimmune disease. Chaired by Professor Dame Barbara Clayton, task force members have provided cutting edge information, which is a must-have reference for a whole range of professionals including dietitians, nutritionists, health visitors, family practitioners, nursing practitioners and many other health professionals.

Cytokines and Autoimmune Diseases

Author : Vijay K. Kuchroo
File Size : 75.11 MB
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Leading researchers synthesize scattered experimental data to help develop an intimate understanding of how cytokines and chemokines are involved in the pathogenesis of autoimmune diseases. The many chapters offer critical reviews the basic mechanisms controlling cytokine induction and regulation, as well as the resulting production of proinflammatory and anti-inflammatory cytokines, the former of which induces organ-specific autoimmune diseases. From the vantage of these insights, they address the role of cytokines in a wide variety of autoimmune diseases, uvetis, encephalomyelitis, multiple sclerosis, human type 1 diabetes, rheumatoid arthritis, SLE, and myasthenia gravis. Authoritative and state-of-the-art, Cytokines and Autoimmune Disease highlights the enormous therapeutic potential of cytokine modulation in the treatment of autoimmune disease.

Development of the Gastrointestinal Tract

Author : Ian R. Sanderson
File Size : 87.36 MB
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The authors chronicle the development of the gastrointestinal system b eginning with the embryology of the gastrointestinal tract through dev elopment of cells to hormones and enzymes. Each section provides detai led explanation of that stage of development so residents and clinicia ns can better understand the interrelationships of each structure. Spe cial attention is given to the latest cellular information and gene pr omoters in the regulation of intestinal development. Coverage of defec ts due to trauma and infections is also included.