Search results for: the-biochemistry-of-retinoid-signaling-ii

The Biochemistry of Retinoid Signaling II

Author : Mary Ann Asson-Batres
File Size : 32.46 MB
Format : PDF, Kindle
Download : 810
Read : 162
Download »
The role of vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes, and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems, and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life. This book series, with chapters authored by experts in every aspect of this complex field, unifies the knowledge base and mechanisms currently known in detailed, engaging, well-illustrated, focused chapters that synthesize information for each specific area. In view of the recent information explosion in this field, it is timely to publish a contemporary, comprehensive, book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action, its role in physiology, development, and continued well-being, and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases. Volume II is divided into nine chapters contributed by prominent experts in their respective fields. Each chapter starts with the history of the area of research. Then, the key findings that contributed to development of the field are described, followed by a detailed look at key findings and progress that are being made in current, ongoing research. Each chapter is concluded with a discussion of the relevance of the research and a perspective on missing pieces and lingering gaps that the author recommends will be important in defining future directions in vitamin A research.

The Biochemistry of Retinoid Signaling III

Author : Mary Ann Asson-Batres
File Size : 50.72 MB
Format : PDF, ePub
Download : 137
Read : 535
Download »
This book covers subjects that have major impacts on society, such as the mechanism of maternal-fetal transfer of vitamin A, and the effects of alcohol on retinoic acid signaling and mammalian embryonic development. There has been an awareness of the importance of consuming vitamins throughout human history, but empirical studies of their physiological role and mode of action only began about 150 years ago. Since then, the biochemical nature of vitamin A and its active derivative, retinoic acid, have been identified and researchers around the globe have investigated retinoic acid’s physiological function in growth processes and in maintaining life Written by leading experts, this book discusses the latest findings and advances in retinoic acid research. It addresses topics such as the role of retinoic acid signaling in a multitude of processes, including limb, heart and respiratory system development, as well as its role in maintaining postnatal organ systems. This book is a valuable resource for scientists involved in vitamin A/retinoic acid research and readers interested in developmental biology.

The Biochemistry of Retinoid Signaling III

Author : Mary Ann Asson-Batres
File Size : 44.96 MB
Format : PDF, ePub
Download : 171
Read : 1112
Download »
This book covers subjects that have major impacts on society, such as the mechanism of maternal-fetal transfer of vitamin A, and the effects of alcohol on retinoic acid signaling and mammalian embryonic development. There has been an awareness of the importance of consuming vitamins throughout human history, but empirical studies of their physiological role and mode of action only began about 150 years ago. Since then, the biochemical nature of vitamin A and its active derivative, retinoic acid, have been identified and researchers around the globe have investigated retinoic acid’s physiological function in growth processes and in maintaining life Written by leading experts, this book discusses the latest findings and advances in retinoic acid research. It addresses topics such as the role of retinoic acid signaling in a multitude of processes, including limb, heart and respiratory system development, as well as its role in maintaining postnatal organ systems. This book is a valuable resource for scientists involved in vitamin A/retinoic acid research and readers interested in developmental biology.

Retinoid Signaling Pathways

Author :
File Size : 49.87 MB
Format : PDF, Kindle
Download : 812
Read : 514
Download »
Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Includes the latest information on retinoid signaling pathways

The Biochemistry of Retinoic Acid Receptors I Structure Activation and Function at the Molecular Level

Author : Mary Ann Asson-Batres
File Size : 73.50 MB
Format : PDF, Kindle
Download : 723
Read : 870
Download »
A role for vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life. This book series, with chapters authored by experts in every aspect of this complex field, unifies the knowledge base and mechanisms currently known in detailed, engaging, well-illustrated, focused chapters that synthesize information for each specific area. In view of the recent explosion in this field, it is timely to publish a contemporary, comprehensive, book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action, its role in physiology, development and continued well-being and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases. VOLUME I: Here, we present the first volume of a multi-volume series on Retinoic Acid Signaling that will cover all aspects of this broad and diverse field. One aim of Volume I is to present a compilation of topics related to the biochemistry of nuclear retinoic acid receptors, from their architecture when bound to DNA and associated with their coregulators to their ability to regulate target gene transcription. A second aim is to provide insight into recent advances that have been made in identifying novel targets and non-genomic effects of retinoic acid. Volume I is divided into ten chapters contributed by prominent experts in their respective fields. Each chapter starts with the history of the area of research. Then, the key findings that contributed to development of the field are described, followed by a detailed look at key findings and progress that are being made in current, ongoing research. Each chapter is concluded with a discussion of the relevance of the research and a perspective on missing pieces and lingering gaps that the author recommends will be important in defining future directions in vitamin A research.

Retinoids

Author : Heinz Nau
File Size : 64.74 MB
Format : PDF, Mobi
Download : 807
Read : 261
Download »
In the future' the decade of the 1990s will likely be viewed as a Golden Age for retinoid research. There have been unprecedented research gains in the understanding of retinoid actions and physiology; since the retinoid nuclear receptors were first identified and the importance of retinoic acid in develop mental processes was first broadly recognized in the late 1980s. Between then and now, our knowledge of retinoid action has evolved from one of a near complete lack of understanding of how retinoids act within cells to one of sophisticated understanding of the molecular processes through which retinoids modulate transcription. In this volume, we have tried to provide a comprehensive update of the present understanding of retinoid actions, with an emphasis on re cent advances. The initial chapters of the volume, or Section A, focus on the physicochemical properties and metabolism of naturally occurring retinoids: - N OY provides an uncommonly encountered view of retinoid effects from the perspective of the physiochemical properties of retinoids. - V AKIANI and BUCK lend a perspective on the biological occurrence and actions of retro- and anhydro-retinoids. Section B considers both the retinoid nuclear receptors and their mechanisms of action as well as synthetic retinoids that have been used exper imentally to provide mechanistic insights into receptor actions and have potential therapeutic use for treating disease: - PIEDRAFITA and PFAHL provide a comprehensive review of retinoid nuclear receptor biochemistry and molecular biology.

The Biochemistry of Retinoic Acid Receptors I Structure Activation and Function at the Molecular Level

Author : Mary Ann Asson-Batres
File Size : 31.53 MB
Format : PDF, Kindle
Download : 544
Read : 519
Download »
A role for vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life. This book series, with chapters authored by experts in every aspect of this complex field, unifies the knowledge base and mechanisms currently known in detailed, engaging, well-illustrated, focused chapters that synthesize information for each specific area. In view of the recent explosion in this field, it is timely to publish a contemporary, comprehensive, book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action, its role in physiology, development and continued well-being and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases. VOLUME I: Here, we present the first volume of a multi-volume series on Retinoic Acid Signaling that will cover all aspects of this broad and diverse field. One aim of Volume I is to present a compilation of topics related to the biochemistry of nuclear retinoic acid receptors, from their architecture when bound to DNA and associated with their coregulators to their ability to regulate target gene transcription. A second aim is to provide insight into recent advances that have been made in identifying novel targets and non-genomic effects of retinoic acid. Volume I is divided into ten chapters contributed by prominent experts in their respective fields. Each chapter starts with the history of the area of research. Then, the key findings that contributed to development of the field are described, followed by a detailed look at key findings and progress that are being made in current, ongoing research. Each chapter is concluded with a discussion of the relevance of the research and a perspective on missing pieces and lingering gaps that the author recommends will be important in defining future directions in vitamin A research.

The Retinoids

Author : Karen Niederreither
File Size : 63.4 MB
Format : PDF, Kindle
Download : 712
Read : 1267
Download »
The second editor's surname is Niederreither, but is misspelled on the title page.

CBP

Author :
File Size : 39.49 MB
Format : PDF, Docs
Download : 425
Read : 992
Download »

Regulation of Chick CYP26 by Developmental Signaling Pathways

Author : Eduardo Martinez-Ceballos
File Size : 74.96 MB
Format : PDF, Mobi
Download : 215
Read : 1241
Download »

The Role of Tetramers of the Retinoid X Receptor in Retinoid Signaling

Author : Alexander Henricus Kersten
File Size : 76.77 MB
Format : PDF, Kindle
Download : 473
Read : 832
Download »
Taken together, the results described in this dissertation suggest that ligand-induced dissociation of RXR tetramers may comprise the initial step in transcription activation mediated by this receptor.

Ubiquitous Ablation of Retinol Dehydrogenase retSDR8 in Mus Musculus

Author : Hua Tran
File Size : 88.68 MB
Format : PDF, Mobi
Download : 177
Read : 299
Download »

Biochemistry and Cell Biology

Author :
File Size : 56.76 MB
Format : PDF, ePub
Download : 488
Read : 444
Download »

Tissue Restricted Disruption of Retinoid Signaling Using Cre LoxP

Author : Esther Merki
File Size : 64.93 MB
Format : PDF, Mobi
Download : 170
Read : 205
Download »

Molecular and Developmental Biology of Cartilage

Author : Benoit De Crombrugghe
File Size : 48.2 MB
Format : PDF, Kindle
Download : 764
Read : 1107
Download »
Drawn from the proceedings of a New York Academy of Sciences Conference, September 27-30, 1995, this book presents 21 papers related to cartilage research from various perspectives. The contributions are from scientists with a common interest in cartilage pathophysiology, and with different backgrounds in human genetics, cellular and molecular biology, embryology and structural biology of extracellular matrix components.

Relationship Between Retinoic Acid and Fibroblast Growth Factor 2 in Vertebrate Limb Development

Author : Rosemarie Kirwin
File Size : 81.48 MB
Format : PDF, Kindle
Download : 304
Read : 555
Download »

Cancer Forum

Author :
File Size : 26.8 MB
Format : PDF, ePub, Mobi
Download : 634
Read : 554
Download »

Cancer Research

Author :
File Size : 77.11 MB
Format : PDF, ePub, Mobi
Download : 319
Read : 842
Download »

Foundations of modern biochemistry

Author : Margery G. Ord
File Size : 27.36 MB
Format : PDF, ePub, Mobi
Download : 357
Read : 1107
Download »

Cambridge Scientific Biochemistry Abstracts

Author :
File Size : 26.36 MB
Format : PDF
Download : 666
Read : 1012
Download »