Search results for: therapeutic-nuclear-medicine

Therapeutic Nuclear Medicine

Author : Richard P. Baum
File Size : 62.8 MB
Format : PDF, ePub, Docs
Download : 301
Read : 423
Download »
The recent revolution in molecular biology offers exciting new opportunities for targeted radionuclide therapy. This up-to-date, comprehensive book, written by world-renowned experts, discusses the basic principles of radionuclide therapy, explores in detail the available treatments, explains the regulatory requirements, and examines likely future developments. The full range of clinical applications is considered, including thyroid cancer, hematological malignancies, brain tumors, liver cancer, bone and joint disease, and neuroendocrine tumors. The combination of theoretical background and practical information will provide the reader with all the knowledge required to administer radionuclide therapy safely and effectively in the individual patient. Careful attention is also paid to the role of the therapeutic nuclear physician in coordinating a diverse multidisciplinary team, which is central to the safe provision of treatment.

Diagnostic Nuclear Medicine and Radionuclide Therapy

Author : Stefano Fanti
File Size : 60.14 MB
Format : PDF, ePub
Download : 608
Read : 300
Download »
Nuclear medicine is a medical imaging specialty involving the use of radioactive compounds for diagnostic and therapeutic purposes. As a medical branch, it is considered part of Diagnostic Imaging, but differs substantially from Radiology with respect to the source of the radiation made visible by the diagnostic devices. Nuclear medicine adopts also some types of radioactive emissions for therapeutic purposes, allowing the employment of the metabolic properties of the radiopharmaceuticals for the cure of certain clinical conditions and malignant diseases. Nuclear medicine is a relatively recent discipline and owes its origins to the discovery of natural radioactivity and the development of the first instruments for medical diagnostics. From the introduction of the first gamma camera of Anger, the technology has greatly improved. The evolution has led to the development of SPECT and PET technology and in the recent years to the introduction of hybrid tomographs allowing the combination in one session of both functional and morphological images. The purpose of this textbook is to illustrate synthetically the principals of nuclear medicine diagnostics, with reference both to the technical part and main clinical indications. The booklet is addressed primarily to the degree courses for technologists, but can be reasonably used in other courses and medical training programs where there is necessity for relatively simple, yet complete and clinically relevant concepts of nuclear medicine discipline. As a complement, the manuscript will end with a dedicated section summarizing some concepts of nuclear medicine therapy.

Radiopharmaceuticals for Therapy

Author : F. F. (Russ) Knapp
File Size : 40.90 MB
Format : PDF, ePub, Docs
Download : 684
Read : 446
Download »
This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.

Diagnostic Nuclear Medicine and Radionuclide Therapy

Author : Stefano Fanti
File Size : 81.34 MB
Format : PDF, ePub
Download : 390
Read : 831
Download »
Nuclear medicine is a medical imaging specialty involving the use of radioactive compounds for diagnostic and therapeutic purposes. As a medical branch, it is considered part of Diagnostic Imaging, but differs substantially from Radiology with respect to the source of the radiation made visible by the diagnostic devices. Nuclear medicine adopts also some types of radioactive emissions for therapeutic purposes, allowing the employment of the metabolic properties of the radiopharmaceuticals for the cure of certain clinical conditions and malignant diseases. Nuclear medicine is a relatively recent discipline and owes its origins to the discovery of natural radioactivity and the development of the first instruments for medical diagnostics. From the introduction of the first gamma camera of Anger, the technology has greatly improved. The evolution has led to the development of SPECT and PET technology and in the recent years to the introduction of hybrid tomographs allowing the combination in one session of both functional and morphological images. The purpose of this textbook is to illustrate synthetically the principals of nuclear medicine diagnostics, with reference both to the technical part and main clinical indications. The booklet is addressed primarily to the degree courses for technologists, but can be reasonably used in other courses and medical training programs where there is necessity for relatively simple, yet complete and clinically relevant concepts of nuclear medicine discipline. As a complement, the manuscript will end with a dedicated section summarizing some concepts of nuclear medicine therapy.

A Concise Guide to Nuclear Medicine

Author : Abdelhamid H. Elgazzar
File Size : 40.77 MB
Format : PDF
Download : 274
Read : 906
Download »
Nuclear medicine is an important component of modern medicine. This easy-to-use book is designed to acquaint readers with the basic principles of nuclear medicine, the instrumentation used, the gamut of procedures available, and the basis for selecting specific diagnostic or therapeutic procedures and interpreting results. After an introductory chapter on the history, technical basis, and scope of nuclear medicine, a series of chapters are devoted to the application of nuclear medicine techniques in the different body systems. In addition, the use of nuclear medicine methods within oncology is carefully examined, covering diagnosis, staging, assessment of treatment response, radiotherapy planning, and the sentinel node technique. The book concludes with a chapter devoted to nuclear medicine therapy. This practical and up-to-date guide to nuclear medicine is ideal for beginners and will also help professionals who need to retrieve useful information rapidly.

Diagnostic and Therapeutic Nuclear Medicine for Neuroendocrine Tumors

Author : Karel Pacak
File Size : 64.42 MB
Format : PDF, ePub, Mobi
Download : 413
Read : 666
Download »
Based on the most novel approaches and cutting-edge clinical and scientific information regarding radionuclide imaging and therapies for neuroendocrine tumors, this clinical guidebook represents a unique collaborative effort between endocrinologists, nuclear physicians, oncologists, surgeons, physicists, radio-pharmacists and geneticists. It begins with the embryology, classification and molecular genetics of gastroenteropancreatic neuroendocrine tumors and carcinoids, chromaffin cell tumors, and MEN1- and MEN2-related tumors. Following a chapter on radiopharmaceuticals in neuroendocrine imaging, it turns to the physics and technology of current and cutting-edge radiology, including SPECT/CT and PET/CT and PET/MR. Discussing of radionuclide imaging covers the tumors mentioned above, as well as pulmonary and thymic neuroendocrine tumors and medullary thyroid carcinoma. A presentation of radionuclide therapies follows, including 131I-MIBG therapy, somatostatin receptor-based therapy, and alpha radionuclide therapy, as well as the role of nanoparticles. Comprehensive and up-to-date, Diagnostic and Therapeutic Nuclear Medicine for Neuroendocrine Tumors will assist and guide physicians who encounter patients with these conditions, either from a diagnostic or therapeutic standpoint, and particularly emphasizes the current and emerging medical devices and imaging and therapeutic options.

Guide for Diagnostic Nuclear Medicine and Radiopharmaceutical Therapy

Author : Jeffry A. Siegel
File Size : 89.79 MB
Format : PDF, ePub, Docs
Download : 505
Read : 1186
Download »

Nuclear Medicine

Author : Richard Zimmermann
File Size : 70.44 MB
Format : PDF, ePub
Download : 146
Read : 470
Download »
Nuclear medicine is a growing specialized medical field in which radiopharmaceuticals, i.e. drugs associated to radioactivity, are used for diagnostic or therapeutic purposes. Since 1942, nuclear medicine has progressed in such a way that it became a major diagnostic tool in hospitals. The past ten years have seen the introduction of major technical breakthroughs which will considerably modify the landscape of cancer treatment. Once injected to the patient, the radiopharmaceutical drug aims at the tumour cell – including metastases – selectively, settles there, and emits radiation. Depending on the radiation type, the drug will either help identify the cells or destroy them. Applications are not limited to oncology; indeed, nuclear medicine has found interesting applications in cardiology and neurology as well. The new millennium saw the introduction of the Hybrid imaging technology PET/CT which combines the Positron Emission Tomography (PET) modality with conventional high quality x-ray imaging. It took another two years until PET could be combined with Magnetic Resonance Imaging (MRI) in the hybrid equipment PET/MR. New tracers (drugs for diagnosis) also came on the market with different diseases as targets, such as prostate cancer, neuroendocrine tumours, or Alzheimer’s disease. But the recent introduction of radiotherapeutics in the treatment of cancer has brought major changes on the market, for they can be much more powerful and specific than chemotherapeutics or external radiation therapy. Combining radiodiagnostics to select positive responders to a treatment with efficient radiotherapeutics opens a highway for the development of theranostics, another word for personalized medicine. This scientific book aims to introduce nuclear medicine to a larger audience, pointing out, among other things, the difficulties met by both physicians and patients when trying to access new technologies. This second edition shows how much progress has been made over the past ten years since the original book was published, and how much can be expected for patients within the next few years.

Nuclear Medicine Therapy

Author : Janet F. Eary
File Size : 33.23 MB
Format : PDF, ePub
Download : 126
Read : 767
Download »
One in three of the 30 million Americans who are hospitalized are diagnosed or treated with nuclear medicine techniques. This text provides a succinct overview and detailed set of procedures and considerations for patient therapy with unsealed radioactivity sources. Serving as a complete literature reference for therapy with radiopharmaceuticals c

Quantitative Analysis in Nuclear Medicine Imaging

Author : Habib Zaidi
File Size : 84.80 MB
Format : PDF, ePub, Docs
Download : 939
Read : 636
Download »
This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and - crease in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G. de Hevesy, quantitative imaging has only recently emerged as a promising approach for diagnosis and therapy of many diseases. An effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine instrumentation and dual-modality imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. A brief overview of each chapter is provided below. Chapter 1 presents a general overview of nuclear medicine imaging physics and instrumentation including planar scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Nowadays, patients’ diagnosis and therapy is rarely done without the use of imaging technology. As such, imaging considerations are incorporated in almost every chapter of the book. The development of dual-modality - aging systems is an emerging research field, which is addressed in chapter 2.