A Very Short Introduction

• Author: Dorothy H. Crawford
• Publisher: Oxford University Press
• ISBN: 0198811713
• Category: Medical virology
• Page: 158
• View: 8535

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Viruses are big news. From pandemics such as HIV, swine flu, and SARS, we are constantly being bombarded with information about new lethal infections. In this Very Short Introduction, Dorothy Crawford demonstrates from their discovery and the unravelling of their intricate structures, how clever these entities really are.

• Author: Dorothy H. Crawford
• Publisher: Oxford University Press
• ISBN: 0199574855
• Category: Medical
• Page: 156
• View: 6644

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Discusses the discovery of viruses, analyzes the threat of viral infections, and considers ways to prevent the emergence of new and devastating viruses.

A Very Short Introduction

• Author: Nicholas P. Money
• Publisher: Oxford University Press, USA
• ISBN: 0199681686
• Category: Science
• Page: 122
• View: 1317

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Describes the expansions of microbiology; it's methods, from traditional microscopy and laboratory culture to the latest genomic analysis.

A Very Short Introduction

• Author: Marta Wayne,Benjamin M. Bolker
• Publisher: Oxford University Press, USA
• ISBN: 0199688931
• Category: Medical
• Page: 144
• View: 7197

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As doctors and biologists have learned, to their dismay, infectious disease is a moving target: new diseases emerge every year, old diseases evolve into new forms, and ecological and socioeconomic upheavals change the transmission pathways by which disease spread. By taking an approach focused on the general evolutionary and ecological dynamics of disease, this Very Short Introduction provides a general conceptual framework for thinking about disease. Ecology and evolution provide the keys to answering the "where", "why", "how", and "what" questions about any particular infectious disease: where did it come from? How is it transmitted from one person to another, and why are some individuals more susceptible than others? What biochemical, ecological, and evolutionary strategies can be used to combat the disease? Is it more effective to block transmission at the population level, or to block infection at the individual level? Through a series of case studies, Benjamin Bolker and Marta L. Wayne introduce the major ideas of infectious disease in a clear and thoughtful way, emphasizing the general principles of infection, the management of outbreaks, and the evolutionary and ecological approaches that are now central to much research about infectious disease. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

• Author: John M. Archibald
• Publisher: Oxford University Press
• ISBN: 0198786204
• Category: Science
• Page: 160
• View: 2920

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Genomics has transformed the biological sciences. From epidemiology and medicine to evolution and forensics, the ability to determine an organism's complete genetic makeup has changed the way science is done and the questions that can be asked of it. Its most celebrated achievement was theHuman Genome Project, a technologically challenging endeavor that took thousands of scientists around the world 13 years and over 3 billion US dollars to complete. In this Very Short Introduction John Archibald explores the science of genomics and its rapidly expanding toolbox. Sequencing a human genome now takes only a few days and costs as little as $1,000. The genomes of simple bacteria and viruses can be sequenced in a matter of hours on a device that fitsin the palm of your hand. The resulting sequences can be used to better understand our biology in health and disease and to 'personalize' medicine. Archibald shows how the field of genomics is on the cusp of another quantum leap; the implications for science and society are profound.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

• Author: Guido Caldarelli,Michele Catanzaro
• Publisher: Oxford University Press
• ISBN: 0199588074
• Category: Computers
• Page: 122
• View: 6071

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Networks are involved in many aspects of everyday life, from food webs in ecology and the spread of pandemics to social networking and public transport. This Very Short Introduction explores the basics of network theory to understand the science of complexity and its importance, using examples from nature, technology, and society, and history.

• Author: Les Iversen
• Publisher: Oxford University Press
• ISBN: 0198745796
• Category:
• Page: 144
• View: 9609

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The twentieth century saw a remarkable upsurge of research on drugs, with major advances in the treatment of bacterial and viral infections, heart disease, stomach ulcers, cancer, and metal illnesses. These, along with the introduction of the oral contraceptive, have altered all of our lives. There has also been an increase in the recreational use and abuse of drugs in the Western world. This Very Short Introduction, in its second edition, gives a non-technical account of how drugs work in the body. Reviewing both legal (alcohol, nicotine, and caffeine) and illegal drugs, Les Iversen disscusses why some are addictive, and whether drug laws need reform. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

• Author: Alan Whiteside
• Publisher: Oxford University Press
• ISBN: 0198727496
• Category: Medical
• Page: 152
• View: 5322

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In 2008 it was believed that HIV/AIDS was without doubt the worst epidemic to hit humankind since the Black Death. The first case was identified in 1981; by 2004 it was estimated that about 40 million people were living with the disease, and about 20 million had died. Yet the outlook today is a little brighter. Although HIV/ AIDS continues to be a pressing public health issue the epidemic has stabilised globally, and it has become evident it is not, nor will it be, a global issue. The worst affected regions are southern and eastern Africa. Elsewhere, HIV is found in specific, usually, marginalised populations, for example intravenous drug users in Russia. Although there still remains no cure for HIV, there have been unprecedented breakthroughs in understanding the disease and developing drugs. Access to treatment over the last ten years has turned AIDS into a chronic disease, although it is still a challenge to make antiviral treatment available to all that require it. We also have new evidence that treatment greatly reduces infectivity, and this has led to the movement of 'Treatment as Prevention'. In this Very Short Introduction Alan Whiteside provides an introduction to AIDS, tackling the science, the international and local politics, the fascinating demographics, and the devastating consequences of the disease. He looks at the problems a developing international 'AIDS fatigue' poses to funding for sufferers, but also shows how domestic resources are increasingly being mobilised, despite the stabilisation of international funding. Finally Whiteside considers how the need to understand and change our behaviour has caused us to reassess what it means to be human and how we should operate in the globalizing world. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

• Author: Paul Klenerman
• Publisher: Oxford University Press
• ISBN: 019875390X
• Category: Medical
• Page: 144
• View: 4728

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The immune system is central to human health and the focus of much medical research. Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine. In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. The immune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called "innate" immune responses, which react very fast to infection, and "adaptive" immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading to serious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the "Immune system v2.o" - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

• Author: Rodolfo Saracci
• Publisher: Oxford University Press
• ISBN: 019954333X
• Category: Medical
• Page: 145
• View: 7255

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Epidemiology is the study of the changing patterns of disease. It is a vital field, central to the health of society, to the identification of causes of disease, and to their management and prevention. This Very Short Introduction dispels some of the myths relating to clinical trials, vaccination campaigns, and statistics concerning disease.